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This study found that lichen planopilaris is associated with three core molecular pathways, which may inform new therapeutic strategies for scarring alopecia, including unique pathways like ABC transporters specific to LPP.

In this study, researchers found that CCCA in women of African descent is associated with molecular changes, including dysregulation of fatty acid metabolism and fibrosis pathways, suggesting potential targets for new treatments.

This study found that activating the Nrf2 pathway in human mast cells effectively suppresses degranulation and inflammation induced by substance P.

This study found that frontal fibrosing alopecia involves distinct molecular changes, such as downregulation of steroid and cholesterol pathways and upregulation of fibrotic and immune response genes, which may help guide treatment strategies.

This review discusses the bidirectional interactions between human mast cells and CD8 T cells in the skin, particularly in the context of disorders like psoriasis, atopic dermatitis, and vitiligo, and reports no new findings.