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research Pathological Skin Scarring: From Mechanism to Targeted Local Therapy

June 2026 in “Preprints.org”

This review examines the mechanisms behind pathological scarring like hypertrophic scars and keloids, highlights the limitations of current treatments, and suggests that biomaterial-enabled delivery of anti-fibrotic statins, such as atorvastatin, may offer a promising therapeutic avenue for managing these scars.

research Deciphering principles of morphogenesis from temporal and spatial patterns on the integument

19 citations , April 2015 in “Developmental Dynamics”

This study reports that dynamic interactions between stem cells and their niche, influenced by macro-environmental factors, regulate regenerative behavior in integument pattern formation.

research Microneedles along with conventional therapies: An in-depth observational review in alopecia areata treatment

1 citations , April 2024 in “Journal of Drug Delivery Science and Technology”

This review examines the use of microneedles for treating alopecia areata, highlighting their ability to enhance drug delivery through the skin by bypassing the outer barrier and promoting hair growth with minimal invasiveness.

research STUDIES ON A SKIN CALCIFYING SYSTEM

12 citations , December 1965 in “Immunology and Cell Biology”

This study found that experimentally induced calcification in rat skin led to rapid and localized mineralization in hair follicles, progressing to more extensive calcification with prior hypercalcemic treatment.

research Integrin signalling regulates YAP/TAZ to control skin homeostasis

266 citations , January 2016 in “Development”

In this study, researchers found that YAP and TAZ, when localized in the nucleus of basal layer cells, are crucial for skin regeneration and hair growth, with their loss leading to slower cell proliferation, hair loss, and impaired wound healing in mice.

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community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp

in Finasteride/Dutasteride 72 upvotes 3 years ago

Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.

community New study on applying minox right after derma stamp

47 upvotes 1 month ago

Microneedling combined with minoxidil and finasteride improves hair growth in androgenetic alopecia, with effectiveness varying by severity. The study was retracted due to concerns about validity and potential AI-generated content.

community REVOLUTION in AUGUST: New possibilities according to Dr. Muñoz (pinacidil, cromakalim, diazoxide and nicorandil)

13 upvotes 1 year ago

Dr. Muñoz's discovery suggests that targeting potassium channels in fibroblasts could reactivate hair growth, offering new treatment possibilities for alopecia. Potential strategies include using minoxidil, diazoxide, and other potassium channel openers, as well as bioelectric devices and direct growth factor applications.

community Sunlight: Does it Stimulate Hair Growth or Hair Loss?

in Research/Science 64 upvotes 2 years ago

The conversation discusses whether sunlight exposure affects hair growth or loss, with mixed anecdotes and theories but no clear consensus. Some suggest moderate sunlight can benefit hair by providing vitamin D, while others doubt its effectiveness compared to treatments like Minoxidil or finasteride.

community Why everyone should be using topical Dutasteride

45 upvotes 3 months ago

Topical Dutasteride, especially in a liposomal base, is recommended for enhanced scalp DHT suppression when used with oral Dutasteride. It is suggested to apply it twice a week for effective results without significant systemic impact.

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