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    Glossary Spironolactone

    medication that blocks hormones to treat hair loss and acne

    Spironolactone, also known by the brand name Aldactone, is a medication primarily used as a diuretic and antihypertensive. It works by blocking the action of aldosterone, a hormone that regulates salt and water balance in the body. In addition to its primary uses, it is also prescribed off-label for conditions like acne and hirsutism (excessive hair growth) due to its anti-androgenic properties, and it can be beneficial in treating certain types of hair loss, such as androgenetic alopecia.

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    1. Spironolactone Blood-pressure and diuretic drug with anti-androgen effects
    2. Dutasteride 5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride
    3. Bicalutamide Nonsteroidal anti-androgen, originally a prostate cancer drug
    4. Estradiol Estrogen hormone, prescribed in tablet, patch and gel forms
    5. Cyproterone a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor