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research Directional Association Between Irritable Bowel Syndrome and Dermatological Disease: A Large-Scale Retrospective Study

December 2025 in “Gastroenterology Insights”

This study found that IBS is positively associated with psoriasis, rosacea, and urticaria, but inversely associated with acne and vitiligo.

research Efficacy, Tolerability, and Superiority of Propylene Glycol-Free, North American Witch-Hazel (Hamamelis virginiana)-Based Solution of 5% Minoxidil Sulfate for the Treatment of Female Androgenetic Alopecia

May 2023 in “International Journal of Trichology”

In this study, 70% of female androgenetic alopecia patients who did not respond to standard minoxidil experienced clinical improvement after switching to a propylene glycol-free, witch hazel-based 5% minoxidil sulfate solution, with the treatment also being well-tolerated.

research Evaluation of affective temperament and anxiety–depression levels of patients with polycystic ovary syndrome

35 citations , July 2015 in “Journal of Affective Disorders”

This study found that women with polycystic ovary syndrome have significantly higher scores for affective temperaments and anxiety and depression than healthy controls, suggesting risk for depressive and anxiety disorders.

research Efficacy of Quadruple-coated Probiotics in Patients With Irritable Bowel Syndrome: A Randomized, Double-blind, Placebo-controlled, Parallel-group Study

January 2024 in “Journal of neurogastroenterology and motility”

This study found that gQlab probiotics improved overall IBS symptoms, particularly in female and constipation-predominant patients, compared to placebo after 4 weeks of treatment.

research Body image, personality profiles and alexithymia in patients with polycystic ovary syndrome (PCOS)

21 citations , November 2018 in “Journal of Psychosomatic Obstetrics & Gynecology”

This study found that women with PCOS exhibited higher levels of alexithymia and body uneasiness compared to healthy controls, affecting their psychological and social well-being.

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Community Join

5 / 100 results

community Don't discount diet for the sake of scalp health. Meds had no effect for 2+ years. 3.5 months since new diet / Shampoo routine.

in Progress Pictures 300 upvotes 2 years ago

Diet and specific shampoo improved scalp health and hair regrowth for someone with seborrheic dermatitis, while medications like Minoxidil and finasteride had no effect. A low-sugar, keto diet was key to their success.

community 2.5 years Minoxidil and HRT, CPA->Lupron +Minox 5%

in Transgender 611 upvotes 1 year ago

The user experienced significant hair regrowth after 2.5 years of using Minoxidil 5% and hormone replacement therapy (HRT) with Lupron, despite initial scalp irritation. Finasteride was ineffective for them.

community Creatine made all my high DHT symptoms return

82 upvotes 1 year ago

Creatine may increase DHT levels, potentially causing symptoms like acne, oily hair, and hair shedding. Users report mixed experiences, with some avoiding creatine due to hair loss concerns and others seeing no impact.

community I’m considering stopping finasteride

in Finasteride/Dutasteride 157 upvotes 9 months ago

The user is considering stopping finasteride due to depression, anxiety, and difficulty building muscle, despite its effectiveness in stopping hair loss. Suggestions include reducing the dose, switching to topical solutions, or consulting a doctor for alternatives like dutasteride or RU58841.

community The Cure isn't 5 years away; it's already here.

in Research/Science 1005 upvotes 1 year ago

PP405 is a new topical treatment for hair loss, showing promise in trials but still requires finasteride for maintenance. There is skepticism about its effectiveness and safety, with concerns about needing finasteride to maintain results.

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Learn

6 / 800 results

learn Neem Oil

Oil from the neem tree, used in traditional remedies

learn Peppermint

Can peppermint irritate the scalp if used daily? Peppermint can irritate the scalp if used daily, especially in sensitive individuals.

learn capsicum

Is capsicum safe for sensitive scalps or inflammatory hair loss? Capsicum may irritate sensitive scalps and worsen inflammatory hair loss.

learn Salicylic acid

Is it safe to use salicylic acid on sensitive or irritated scalps? Salicylic acid can irritate a sensitive or broken scalp. People allergic to aspirin should not use it, and rare poisoning has been reported after use on large areas of skin.

learn Tea tree

Are there limitations or considerations when using tea tree oil in hair loss or scalp treatment products? Tea tree oil can irritate the skin and cause allergy, is poisonous if swallowed, and should be kept away from children and cats. No study has shown that it treats hair loss.

learn Citric Acid

Does citric acid dry out or nourish the scalp? At the low levels used to set a product's pH, citric acid neither nourishes nor meaningfully dries the scalp. Concentrated or homemade acidic mixtures can irritate it.

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Clinics

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All 500 clinic results →

Experts

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Trichologist
Kirsten J. Scalp
Greenville, SC, United States

Kirsten J. Scalp