Directional Association Between Irritable Bowel Syndrome and Dermatological Disease: A Large-Scale Retrospective Study

    December 2025 in “ Gastroenterology Insights ”
    A. Liu, Naofumi Matsuno, H. F. Nelson … David M. Pariser
    Studysummary This study found that IBS is positively associated with psoriasis, rosacea, and urticaria, but inversely associated with acne and vitiligo.
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    Research cited in this study 8

    1. Immune-Mediated Disorders in Patients With Alopecia Areata: Systematic Review and Meta-Analysis International Journal of Dermatology · 2025
    2. Pathogenesis of Alopecia Areata and Vitiligo: Commonalities and Differences International journal of molecular sciences · 2024
    3. The Role of the Gut Microbiome and Microbial Dysbiosis in Common Skin Diseases International journal of molecular sciences · 2024
    4. Comorbid Conditions Associated With Alopecia Areata: A Systematic Review and Meta-Analysis American Journal of Clinical Dermatology · 2023
    5. Assessment of a Bidirectional Association Between Major Depressive Disorder and Alopecia Areata JAMA Dermatology · 2019
    6. Acne and Hidradenitis Suppurativa British journal of dermatology/British journal of dermatology, Supplement · 2018
    7. Understanding Autoimmunity of Vitiligo and Alopecia Areata Current opinion in pediatrics, with evaluated MEDLINE/Current opinion in pediatrics · 2016
    8. Vitiligo and Alopecia Areata: Apples and Oranges? Experimental Dermatology · 2013