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    Glossary Intestinal Stem Cells

    specialized cells in the gut that regenerate intestinal lining

    Intestinal Stem Cells (ISCs) are specialized cells located in the lining of the intestines that have the ability to self-renew and differentiate into various types of cells that make up the intestinal epithelium. These cells are crucial for maintaining the integrity and function of the gut by continuously replenishing the intestinal lining, which is constantly being worn down by digestive processes.

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    1. Somatic stem cell heterogeneity: diversity in the blood, skin and intestinal stem cell compartments Nature Reviews Molecular Cell Biology · 2015 · 137 citations
    2. Metabolic Teamwork in the Stem Cell Niche Cell metabolism · 2017 · 14 citations
    3. Stem cell niche: from concept to reality Pigment Cell & Melanoma Research · 2012 · 1 citations
    4. Compartmentalized organization: a common and required feature of stem cell niches? Development · 2010 · 63 citations
    5. Dormancy in the stem cell niche Stem Cell Research & Therapy · 2012 · 29 citations
    6. Signaling in the stem cell niche: regulating cell fate, function and plasticity Development · 2018 · 139 citations
    7. Stem Cells in the Wild: Understanding the World of Stem Cells through Intravital Imaging Cell Stem Cell · 2014 · 17 citations
    8. Stem Cells in the Body 2017
    9. A family business: stem cell progeny join the niche to regulate homeostasis Nature Reviews Molecular Cell Biology · 2012 · 254 citations
    10. Stretching the limits: from homeostasis to stem cell plasticity in wound healing and cancer Nature Reviews Genetics · 2018 · 124 citations
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