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GlossaryIntestinal Stem Cells

specialized cells in the gut that regenerate intestinal lining

Intestinal Stem Cells (ISCs) are specialized cells located in the lining of the intestines that have the ability to self-renew and differentiate into various types of cells that make up the intestinal epithelium. These cells are crucial for maintaining the integrity and function of the gut by continuously replenishing the intestinal lining, which is constantly being worn down by digestive processes.

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community The theory that explains everything. Please help me make this big!

in Research/Science 2447 upvotes 3 years ago

The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 97 upvotes 4 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

in Research/Science 14 upvotes 6 months ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community Don't postpone treatments now with the allure and promise of future treatments.

in Treatment 91 upvotes 4 years ago

The conversation advises against waiting for future hair loss treatments and suggests using proven treatments like Finasteride and Minoxidil. Some users regret not starting treatment earlier, while others discuss the effectiveness and safety of current treatments and the potential of microneedling.

community Hair follicle cloning is already possible

in Chat 38 upvotes 2 months ago

Hair follicle cloning is claimed to be possible but not widely available due to potential safety issues, such as cancer risks. Current treatments like finasteride and dutasteride are not effective for everyone, and there is frustration over limited access to these medications.

community A Summary of the Latest Research regarding PFS, and How Supplementing Allopregnanolone Might Protect Against It

in Chat 6 upvotes 9 months ago

Post Finasteride Syndrome (PFS) may result from epigenetic changes and gut microbiota alterations. Supplementing with Allopregnanolone might protect against these adverse effects.

community 1.5 years on fin/min progress pics, thoughts would be great!

in Progress Pictures 69 upvotes 3 years ago

A 42-year-old male shared his 1.5-year hair regrowth progress using 1.25mg finasteride daily and regular doses of minoxidil twice a day, and recently started using the Derminator 2. He also mentioned his battle with cancer and Cushing's syndrome, which affected his weight and hair.

community The link between hair loss and gut health

in Research/Science 59 upvotes 4 years ago

The conversation discusses the potential link between gut health and hair loss, with personal experiences of hair thinning and stomach issues shared. Some individuals found no success with common hair loss treatments like Minoxidil and Finasteride and are exploring the impact of gut health on hair growth.

community At least my hair is getting thicker. 1.25 oral min

in Is this regrowth? 117 upvotes 7 months ago

The user reports hair thickening after 2 months on 1.25mg oral minoxidil and 1mg oral finasteride, having previously used topical minoxidil with no improvement. Other users suggest taking consistent progress photos and share their own experiences with similar treatments.

community Lost density 60% all over scalp in 120 days (4months)

in Update 10 upvotes 6 months ago

A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.

community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 743 upvotes 2 years ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

community Akkermansia improves testosterone-induced hair growth inhibition.

in Research/Science 3 upvotes 1 year ago

Akkermansia bacteria can improve hair growth inhibited by testosterone, and metformin may increase Akkermansia, which could help with hair loss related to aging, insulin resistance, and inflammation.

community Is Fagron TrichoTest (first genetic test for hair loss) a SCAM?

in Research/Science 9 upvotes 1 year ago

User ronopibf discusses Fagron TrichoTest, a genetic test for hair loss, and seeks opinions on its effectiveness. Some users support the service, while others call it a scam, with prices ranging from $200-$500.

community Today I’m finally starting oral microneedling. About to take my first capsule, so excited!

in Satire 1626 upvotes 3 weeks ago

The conversation humorously discusses starting oral microneedling for hair loss, with mentions of side effects like internal bleeding and abdominal pain. It also references using treatments like minoxidil and finasteride, with exaggerated and satirical comments on their effects.

community Autoimmune disease and balding

in Update 12 upvotes 6 months ago

A user diagnosed with Crohn's disease is concerned it might contribute to balding. They have been using keto shampoo, finasteride, and oral minoxidil, which improved their hair but not significantly.

community Year and 5 months topical fin (ama)

in Progress Pictures 13 upvotes 9 months ago

The conversation discusses a user's experience with topical finasteride for hair loss over a year and five months, including a two-month break due to financial reasons. Another user inquires about increasing their dosage due to lack of progress after three months.

community 25-31 recovery makes my hair almost unmanageable.

in Progress Pictures 17 upvotes 7 months ago

A user shared their hair recovery progress from ages 25-31, attributing success to quitting smoking, minoxidil, microneedling, and hormone therapy. They also mentioned being transgender and using hormone therapy.

community 2 month update. Fin+minox+ketoconazole+dermarolling+mk677+zink&d3

in Progress Pictures 7 upvotes 8 months ago

A user reports significant hair density increase and new growth at the temples after two months of using finasteride, minoxidil, ketoconazole, dermarolling, MK-677, zinc, and vitamin D3, with shedding stopping a week ago. They recently added MK-677 to their regimen.

community Spanish dermatologist suggests sulforaphane for AGA

in Research/Science 13 upvotes 11 months ago

A Spanish dermatologist suggests sulforaphane for androgenetic alopecia (AGA) due to its potential to remove DHT metabolites, though high dosages are needed. A topical formulation might be possible.

community How is it that golden era bodybuilders kept their hair while blasting gear while in the modern era most are bald? I’m convinced there’s something in our food and water causing MPB to speed up

in Satire 729 upvotes 1 year ago

The conversation is about the difference in hair loss between bodybuilders in the "Golden Era" and modern bodybuilders. Some users speculate that factors such as the types and doses of steroids used, genetics, diet, microplastics, and overall health may contribute to hair loss. Hair loss prevention medication and transplants are mentioned as potential treatments.

community Why use finasteride when you can do handstands and take vitamins instead! (☞^o^) ☞

in Satire 363 upvotes 1 year ago

This conversation was a satire post about hair loss treatments, and included a range of different treatments from biotin to handstands. Finasteride and Minoxidil were specifically mentioned as potential treatments that have scientific evidence to support their effectiveness.

community drinking topical minoxidil – extreme hair growth everywhere

in Minoxidil 396 upvotes 2 years ago

At this point. In this conversation, users discussed the risks of drinking topical minoxidil and suggested alternative treatments such as obtaining a prescription for oral minoxidil or finasteride.

community Out of curiosity, why are Finasteride pills formulated as small tablets, while Dutasteride pills are much larger soft gel capsules?

in Finasteride/Dutasteride 41 upvotes 1 week ago

Finasteride and Dutasteride are used for hair loss, with Dutasteride often in gel form for better bioavailability. Switching from Finasteride to Dutasteride is common, with some users combining treatments like Minoxidil for improved results.

community Over 13 months on 5% minoxidil and 6 months on finastride

in Progress Pictures 296 upvotes 1 month ago

A user stopped using 5% minoxidil and finasteride despite positive results to focus on enjoying life without the stress of hair care. They prioritize personal happiness and acceptance over hair maintenance.

community How are people getting DUT so easily?

in Finasteride/Dutasteride 15 upvotes 1 month ago

Dutasteride is hard to get in Europe due to prescription rules, leading some to consider online pharmacies or travel. Users discuss alternatives like private doctors and compare it to finasteride, expressing concerns about side effects and effectiveness.

community Can Fin + Min save my hair? [20M]

in Satire 3155 upvotes 5 months ago

A user is considering using finasteride and minoxidil to address hair loss, particularly at the temples and crown. Responses include encouragement, humor, and additional suggestions like using a derma roller.

community 2 month progress with Minoxidil and Dermaroller

in Minoxidil 412 upvotes 10 months ago

The conversation discusses a user's two-month hair regrowth progress using Minoxidil and a 0.5mm dermaroller. Some suggest adding a 5-alpha-reductase inhibitor like finasteride or dutasteride to maintain the results.

community I just got back from the animal hospital and lost my cat

in Minoxidil 475 upvotes 11 months ago

A user shared a tragic experience where their cat died after being exposed to Minoxidil, warning others of its toxicity to pets. Some users discussed switching to oral hair loss treatments, while others expressed condolences and shared their own concerns and experiences with topical treatments around pets.

community Anyone have experience with natural DHT blockers?

in Finasteride/Dutasteride 7 upvotes 1 year ago

The conversation is about using natural DHT blockers like pumpkin seed oil and saw palmetto extract for hair loss. The user has been using minoxidil, derma rolling, vitamin D, and biotin but is considering finasteride next.

community Sublingual Minoxidil - Cure to Hairloss?

in Minoxidil 583 upvotes 1 year ago

The conversation discusses the potential benefits of sublingual minoxidil for hair loss treatment. It suggests that sublingual minoxidil, which bypasses the liver, may have fewer side effects, greater bioavailability, and could be more effective than oral minoxidil.