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Glossary Interleukin-4

protein that regulates immune responses and inflammation

Interleukin-4 (IL-4) is a type of protein called a cytokine that plays a crucial role in the immune system. It helps regulate the balance of immune responses by promoting the growth and differentiation of certain white blood cells, particularly those involved in allergic reactions and asthma. IL-4 is also involved in the regulation of antibody production, making it important for both immune defense and inflammation.

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White Adipose Tissue Initiates IL-33-Dependent Expression of Interleukin 4/13 in Myeloid Cells During Inflammation

research Das weiße Hautfettgewebe initiiert die IL-33-abhängige Expression von Interleukin 4/13 in myeloischen Zellen während einer Entzündung

August 2024 in “Qucosa (Saxon State and University Library Dresden)”

In this study on mice, researchers observed that dermal white adipose tissue (dWAT) plays a key role in regulating skin inflammation and tissue repair; however, reduced expression of certain cytokines in obese mice may hinder these processes, indicating potential metabolic disruptions in dWAT during inflammation.

research 42905 Role of regulatory T and T-helper 17 cells in patients with acute diffuse and total alopecia

September 2023 in “Journal of the American Academy of Dermatology”

Increased Treg cells and IL-10 may help quick recovery in acute diffuse and total alopecia.

A New Immune-Biochemical Study To Identify Indicators Of The Response Of Infertile Polycystic Ovary Syndrome Patients To Metformin Treatment

research A New Immune-Biochemical Study To Identify Indicators Of The Response Of Infertile Polycystic Ovary Syndrome Patients To Metformin Treatment

June 2025 in “International Journal of Environmental Sciences”

In this study, researchers found that serum levels of integrin, CLEC10A, and interleukin-42 significantly differed between PCOS patients treated with infertility drugs and untreated PCOS patients when compared to healthy controls, suggesting these biomarkers could help differentiate treatment status in PCOS.

research Alopecia Areata in Severe Atopic Dermatitis Treated With Dupilumab

49 citations , December 2018 in “Journal of Investigational Allergology and Clinical Immunology”

Dupilumab may cause hair loss in some patients with severe atopic dermatitis.

ADM Scaffolds Generate a Pro-Regenerative Microenvironment During Full-Thickness Cutaneous Wound Healing Through M2 Macrophage Polarization via Lamtor1

research ADM Scaffolds Generate a Pro-regenerative Microenvironment During Full-Thickness Cutaneous Wound Healing Through M2 Macrophage Polarization via Lamtor1

17 citations , June 2018 in “Frontiers in Physiology”

This study found that acellular dermal matrix scaffolds may facilitate full-thickness skin wound healing by promoting a pro-regenerative immune response through M2 macrophage polarization via the Lamtor1 pathway.

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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