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GlossaryInterleukin-1

protein that regulates immune and inflammatory responses

Interleukin-1 (IL-1) is a type of protein called a cytokine that plays a crucial role in the body's immune and inflammatory responses. It helps regulate immune reactions by promoting the activation of white blood cells and the production of other inflammatory molecules. Elevated levels of IL-1 are often associated with conditions like autoimmune diseases and chronic inflammation.

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research Minoxidil Downregulates Interleukin-1 Alpha Gene Expression in HaCaT Cells

16 citations, January 2018 in “International Journal of Trichology”

Minoxidil may help treat hair loss by reducing inflammation-related gene activity in skin cells.

Injury-Induced Interleukin-1 Alpha Promotes Lgr5 Hair Follicle Stem Cells Regeneration and Proliferation via Regulating Regenerative Microenvironment in Mice

research Injury-Induced Interleukin-1 Alpha Promotes Lgr5 Hair Follicle Stem Cells Regeneration and Proliferation via Regulating Regenerative Microenvironment in Mice

7 citations, February 2023 in “Inflammation and Regeneration”

The protein interleukin-1 alpha helps regenerate hair follicles and increase stem cell growth in mice.

research Wound Healing Protects Against Chemotherapy-Induced Alopecia in Young Rats via Up-Regulating Interleukin-1β-Mediated Signaling

3 citations, May 2017 in “Heliyon”

Wound healing can help prevent hair loss from chemotherapy in young rats by increasing interleukin-1β signaling.

research Serum Levels of Interleukin-1 (IL-1α, IL-1β) in Patients with Alopecia Areata

1 citations, July 2012 in “Nasza Dermatologia Online”

IL-1α levels are higher in alopecia areata patients, suggesting a role in the disease.

Interleukin-1 and Keratinocyte Growth Factor/Fibroblast Growth Factor-7 Gene Expression in Skin Experimental Irritant Contact Dermatitis Mouse Model Treated with Aqueous Extract of Trachyspermum Copticum Seeds

research Interleukin-1 and Keratinocyte Growth Factor/Fibroblast Growth Factor-7 Gene Expression in Skin Experimental Irritant Contact Dermatitis Mouse Model Treated with Aqueous Extract of Trachyspermum Copticum Seeds

August 2018

Ajwain seed extract improved skin healing and hair growth in a mouse skin irritation model.

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community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

in Research/Science 14 upvotes 5 months ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 449 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.