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    Did you mean Interleukin-1 Receptor Antagonist?
    Glossary Interleukin-1 Receptor Antagonist

    naturally occurring protein that inhibits inflammatory molecule interleukin-1

    Interleukin-1 Receptor Antagonist (IL-1RA) is a naturally occurring protein that inhibits the activity of interleukin-1 (IL-1), a molecule involved in inflammatory responses. By blocking IL-1 from binding to its receptor, IL-1RA helps reduce inflammation and is used in treatments for conditions like rheumatoid arthritis and other inflammatory diseases.

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    1. Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice Cancer Research · 2009 · 53 citations
    2. Data from Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice 2023
    3. Data from Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice 2023
    4. Skin toxicity caused by EGFR antagonists—An autoinflammatory condition triggered by deregulated IL‐1 signaling? Journal of Cellular Physiology · 2008 · 19 citations
    5. Erlotinib-Induced Skin Inflammation Is IL-1 Mediated in KC-Tie2 Mice and Human Skin Organ Culture 2014 · 15 citations
    6. IL-1 alpha inhibits human hair follicle growth and hair fiber production in whole-organ cultures. PubMed · 1993 · 30 citations
    7. The TRPM5 Antagonist Triphenylphosphine Oxide Increases Sebaceous Lipogenesis and Modulates Immune Phenotype of Human Sebocytes in a TRPM5‐Independent Manner Experimental Dermatology · 2025
    8. 17β-estradiol Inhibits the Production of RANTES in Human Keratinocytes Journal of Investigative Dermatology · 2003 · 56 citations
    9. THE PATHOGENESIS OF ALOPECIA AREATA Dermatologic Clinics · 1996 · 89 citations
    10. FOLLICULAR LIPOSOMAL DELIVERY SYSTEMS Journal of liposome research · 2002 · 55 citations
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    1. NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress Reddit · 9 Jun 2024

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