Search

for
Search:

Research

5 / 1000+ results

research Reliability of Histopathology for the Early Recognition of Fibrosis in Traction Alopecia: Correlation with Clinical Severity

5 citations , June 2019 in “Dermatopathology”

This study found poor agreement among dermatopathologists in identifying and grading fibrosis in traction alopecia, suggesting the need for better diagnostic methods for early fibrosis detection.

research Frontal fibrosing alopecia versus lichen planopilaris: a clinicopathological study

126 citations , April 2006 in “International Journal of Dermatology”

This study found that frontal fibrosing alopecia and lichen planopilaris have similar histopathological features, but FFA exhibits more prominent apoptosis and less inflammation with spared interfollicular epidermis.

research Fibrosing Alopecia in a Pattern Distribution

September 2021 in “CRC Press eBooks”

This review discusses fibrosing alopecia in a pattern distribution and highlights diagnostic features, but reports no new clinical results; the authors emphasize the value of trichoscopy and histology in diagnosis.

research Differential expression of mTOR signaling pathway proteins in lichen planopilaris and frontal fibrosing alopecia

5 citations , September 2018 in “Acta histochemica”

This study observed that proteins in the mTOR signaling pathway are expressed differently in the hair follicles of patients with lichen planopilaris and frontal fibrosing alopecia, suggesting a role in the pathogenesis of these conditions.

research A Cross-sectional Observational Study to Correlate the Trichoscopic Findings of Female Pattern Hair Loss with the Disease Severity and Underlying Histopathological Changes

November 2023 in “International Journal of Trichology”

In this study, researchers observed that trichoscopy could reliably identify features such as anisotrichosis and signs associated with inflammation and fibrosis in female pattern hair loss, which may aid in assessing disease severity and guiding treatment decisions.

View more "interfollicular fibrosis" in research →

Learn

4 / 800 results

learn Follicusan

learn Trichogen® (foligain)

learn Follistatin

What is follistatin, and how does it influence hair follicle growth and regeneration? Follistatin blocks activin and related growth-inhibiting proteins, which mouse studies link to hair follicle development and cycling; the only verifiable human evidence is a single small 2011 phase 1 injection trial, so follistatin remains experimental and is not an approved hair-loss treatment.
Are there any clinical studies supporting follistatin as a hair loss treatment? There is no controlled human trial showing follistatin treats hair loss; the published work is mouse and laboratory biology on the activin/follistatin signalling system, plus one small 2011 phase 1 injection study of a combination product, so follistatin remains experimental and unapproved.

learn Fluocinolone

Can long-term use of Fluocinolone affect the health of hair follicles? There is no long-term human trial measuring what topical fluocinolone does to hair follicles; what is documented is the label's warning about skin atrophy with prolonged use, plus a 2007 mouse study suggesting hair-follicle bulge stem cells do not repair steroid-induced atrophy.

View more "interfollicular fibrosis" in learn →

Community Join

5 / 1000+ results

community Dutasteride Isn't Working? Get a Scalp Biopsy NOW

in Finasteride/Dutasteride 19 upvotes 1 year ago

Dutasteride may not be effective for everyone due to underlying issues, suggesting scalp biopsies for further diagnosis. Users discuss using higher doses of dutasteride, topical treatments, minoxidil, and pyrilutamide for hair loss management.

community Tazarotene shows strong standalone hair regrowth potential, not just a Minoxidil enhancer. Backed by VEGF, HF regeneration, and angiogenesis pathways. Here’s why.

135 upvotes 1 year ago

Tazarotene shows potential as a standalone treatment for hair regrowth by stimulating new hair follicle formation and promoting angiogenesis, similar to microneedling effects. It can be used topically without minoxidil, but users should start with a low concentration to avoid irritation.

community 30-Min Dermatology Visit – Best Questions to Ask About Balding? ( 175$ )

6 upvotes 1 year ago

The conversation discusses hair loss treatments, focusing on finasteride, minoxidil, and other options like PRP and ketoconazole. It highlights the importance of asking specific questions during a dermatology visit to determine the cause of hair loss and appropriate treatments.

community Fibrosing alopecia in a pattern distribution

in Research/Science 14 upvotes 2 years ago

A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.

community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

59 upvotes 6 months ago

Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

View more "interfollicular fibrosis" in community →

Experts

— no results

Try a deeper search in experts →

Clinics

— no results

Try a deeper search in clinics →