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research Der Effekt von oxidiertem Low Density Lipoprotein im Vergleich zu Zytokin-induzierter Inflammation auf die Differenzierungseigenschaften von humanen gingivalen mesenchymalen Stammzellen

January 2025 in “Multimedialen Archiv und Publikationsserver der Christian-Albrechts-Universität zu Kiel (Christian-Albrechts-Universität zu Kiel)”

In this study, human gingival mesenchymal stem cells responded differently to inflammation mediated by oxidized low-density lipoprotein (oxLDL) compared to cytokines; oxLDL significantly reduced cell proliferation but had less negative impact on differentiation characteristics.

Finasteride Delays Atherosclerosis Progression and Reduces Hepatic Inflammation in Low-Density Lipoprotein Receptor-Deficient Mice

research Abstract 313: Finasteride Delays Atherosclerosis Progression and Reduces Hepatic Inflammation in Low-density Lipoprotein Receptor-deficient Mice

May 2023 in “Arteriosclerosis, thrombosis, and vascular biology”

In this study, finasteride significantly reduced plasma cholesterol and triglycerides and decreased atherosclerotic lesion burden in mice, suggesting its potential role in delaying cardiovascular disease.

research Correlation between individual inflammation genetic profile and platelet rich plasma efficacy in hair follicle regeneration: a pilot study reveals prognostic value of IL-1a polymorphism.

4 citations , November 2017 in “PubMed”

This pilot study found a correlation between individual genetic inflammation profiles and the effectiveness of PRP treatment for hair regeneration, with differences observed between male and female responses.

research Successful topical minoxidil treatment for hair density and length in trichorhinophalangeal syndrome type 1

January 2024 in “Pediatric Dermatology”

This case study found that a 9-year-old girl with trichorhinophalangeal syndrome type 1 experienced significant improvements in hair density and length after 4 months of topical minoxidil treatment, suggesting its therapeutic potential for this condition.

Recombinant Human Growth Hormone Promotes Burn Wound Repair by Regulating Vascular Endothelial Growth Factor and Microvessel Density

research Recombinant Human Growth Hormone Promotes Burn Wound Repair by Regulating Vascular Endothelial Growth Factor and Micro Vessel Density

January 2024

In this animal study, rats treated with recombinant human growth hormone (at both low and high doses) experienced quicker burn wound healing than controls, with increased micro vessel density and altered expression of vascular endothelial growth factor, alongside changes in oxidative stress and inflammation markers.

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Community Join

5 / 917 results

community Trialing the probiotics BB536, PTA 6475 so you don’t have to

75 upvotes 1 year ago

Probiotics like L. reuteri ATCC PTA 6475 and B. longum BB536 may improve hair growth and density by reducing inflammation and reversing DHT damage. The user is trialing these probiotics personally, ordering them from the U.S. to Canada, and plans to continue if no adverse effects occur.

community Serum based on plant extracts boosts hair growth in weeks.

44 upvotes 11 months ago

A serum containing Centella asiatica extracellular vesicles, IGF-1, FGF-7, and caffeine significantly improved hair thickness, density, length, and reduced hair loss after 56 days. The conversation also discusses how treatments like finasteride, minoxidil, and ketoconazole address different aspects of hair loss by reducing DHT, improving blood flow, and lowering inflammation.

community Shedding stopped and micro inflammation is gone after adding dut 1.5 mg for 1 month

in Update 11 upvotes 9 months ago

Dutasteride 1.5 mg stopped shedding and reduced scalp inflammation in one month, unlike finasteride. The user also uses minoxidil but saw no results until adding dutasteride.

community Diffuse hair shedding + recurrent scalp burning/inflammation — looking for similar experiences

3 weeks ago

The user experienced scalp burning and diffuse hair shedding after surgery, with symptoms worsening due to factors like weather changes and stress. They tried minoxidil and finasteride but stopped due to side effects, and found some relief with corticosteroid scalp treatments while correcting vitamin deficiencies.

community Severe diffuse thinning after scalp inflammation – should I keep fighting or just accept it?

in Finasteride/Dutasteride 4 upvotes 11 months ago

A 23-year-old experiencing severe diffuse thinning after scalp inflammation is considering finasteride as a last resort after stopping minoxidil and using anti-inflammatory medication. Users suggest that inflammation causes temporary shedding and recommend consulting a dermatologist, with some advocating for finasteride as a reliable treatment option.

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Learn

10 / 801 results

learn Cetirizine

How does cetirizine reduce inflammation linked to hair loss? Cetirizine is proposed to lower prostaglandin D2 and raise prostaglandin E2 around hair follicles; three small trials of a compounded 1% topical report modest increases in hair density and shaft thickness, with minoxidil doing better head-to-head. Topical cetirizine is off-label and unapproved for hair loss, and the evidence is too thin to call it effective or safe.

learn Baicapil

Struggling with patchy hair loss like alopecia areata? Baicapil might help by reducing inflammation and reactivating growth. There is no published trial of Baicapil in alopecia areata. The anti-inflammatory and hair-density claims come from the ingredient's manufacturer and from laboratory work on its plant extracts, in people with androgenetic-type hair loss rather than autoimmune patchy hair loss.

learn Baricitinib

JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Low Level Laser Therapy

laser therapy for anti-inflammatory and likely insignificant hair regrowth effects

learn Platelet-Rich Plasma

growth factors taken from your blood and injected into your scalp to stimulate hair

learn Azelaic Acid

acid used for antimicrobial, anti-inflammatory and anti-androgenic properties

learn Omega 3

Did you know omega-3 can lower scalp inflammation that leads to sudden hair loss? Omega-3 can reduce scalp inflammation, potentially preventing sudden hair loss.

learn Ginkgo biloba

Can ginkgo biloba reduce scalp inflammation that contributes to hair loss? Ginkgo biloba may help reduce scalp inflammation, potentially benefiting hair loss.

learn Hydrocortisone

Is hydrocortisone effective for stopping inflammation that blocks hair growth? Sources describe hydrocortisone as a short-course treatment for scalp inflammation such as seborrhoeic dermatitis or eczema, and no verified trial tests it as a hair-regrowth treatment; the corticosteroids used for alopecia areata are the potent prescription ones, and prolonged use of any topical steroid on the scalp risks skin thinning.

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