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      research Analysis of the Penetration of a Caffeine Containing Shampoo Into the Hair Follicles by In Vivo Laser Scanning Microscopy

      26 citations , December 2009 in “Laser Physics”
      The study utilized in vivo laser scanning microscopy to examine the penetration of caffeine from a shampoo into hair follicles. It was found that a 2-minute contact time was sufficient for significant accumulation of caffeine in the follicles, reaching a depth of approximately 200 μm, which is the detection limit of the microscopy used. This depth is where the network of blood capillaries around the follicles begins. Caffeine remained detectable in the follicles even after 24 hours, indicating that hair follicles can serve as a long-term reservoir for topically applied substances like caffeine.

      research Investigation of the Penetration and Storage of a Shampoo Formulation Containing Caffeine into the Hair Follicles by In Vivo Laser Scanning Microscopy

      24 citations , February 2007 in “Laser Physics Letters”
      The study investigated the penetration of a caffeine-containing shampoo into hair follicles using in vivo laser scanning microscopy. It was found that a 2-minute contact time allowed the formulation to penetrate deeply into the follicles and remain for up to 48 hours, even after washing. This highlighted hair follicles as significant targets for drug delivery due to their surrounding capillary network. The study also demonstrated the effectiveness of in vivo laser scanning microscopy in analyzing the dermatopharmacokinetics of topically applied substances.
      Scalp Imaging Techniques

      research Scalp Imaging Techniques

      5 citations , March 2017 in “Laser Physics Letters”
      Different scalp imaging methods are important for studying hair and scalp health and require more volunteers for better evaluation.

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