March 2023 in “International Journal of Applied Pharmaceutics” In this study, researchers formulated a topical gel containing β-sitosterol for alopecia treatment and found it demonstrated good 5 alpha reductase inhibitory activity in vitro, comparable to a commercial product, indicating its potential for further antiandrogenic activity investigation.
September 2017 in “Journal of Investigative Dermatology” This study found that dermal papilla cells exhibit stage-dependent variation in histone methylation during the hair follicle cycle and display distinct chromatin marker expression when transitioning to in vitro culture.
August 2026 in “Regenerative Biomaterials” This review examines human-relevant in vitro models for studying pigmentation disorders, identifying both challenges and advancements in replicating human pigmentation processes and disease-specific pathology in vitro.
188 citations
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October 2012 in “The AAPS Journal” This review discusses strategies for developing semi-solid topical generic products to match the quality of reference-listed drugs, using concepts like quality by design and reverse-engineering, but reports no new results.
26 citations
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July 2006 in “International Journal of Cosmetic Science” This study found that taurine uptake by isolated human hair follicles promoted hair survival and protected against TGF-β1-induced damage in an in vitro setting.