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Glossary Immune Regulation

processes that control immune system activity and balance

Immune Regulation, also known as immune system regulation or regulation of immune response, refers to the complex processes that control the activity and balance of the immune system. This involves mechanisms that activate immune responses to fight infections and diseases, as well as those that suppress these responses to prevent overactivity that could lead to autoimmune diseases, such as alopecia areata, where the immune system mistakenly attacks hair follicles.

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Research

5 / 1000+ results

research A human prenatal skin cell atlas reveals immune cell regulation of skin morphogenesis

October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

This study constructed a comprehensive atlas of prenatal human skin, revealing that innate immune cells, such as macrophages, play a crucial role in skin morphogenesis by interacting with non-immune cells, influencing hair follicle formation and angiogenesis beyond their traditional immune functions.

research 546 Epidermal growth factor receptor as a key regulator of the immune privilege

November 2022 in “Journal of Investigative Dermatology”

This study implicates EGFR as a critical regulator of immune privilege and stem cell quiescence in hair follicles, suggesting a link between EGFR inhibition and inflammation-driven hair loss during cancer therapy.

research Regulation and dysregulation of hair regeneration: aiming for clinical application

2 citations , July 2022 in “Cell Regeneration”

This review discusses the complex interplay of factors controlling hair regeneration and highlights the potential for targeted clinical applications in various hair disorders, while reporting no new clinical results.

research Multi-layered environmental regulation on the homeostasis of stem cells: The saga of hair growth and alopecia

59 citations , February 2012 in “Journal of Dermatological Science”

This review discusses the multiple layers of environmental controls on hair stem cell homeostasis and suggests that targeting these layers could offer safer regenerative medicine therapies without directly using stem cells.

research Regulatory T-Cells: Potential Regulator of Tissue Repair and Regeneration

188 citations , March 2018 in “Frontiers in Immunology”

This review discusses the role of regulatory T-cells in tissue repair and regeneration across various organs and reports no new clinical results.

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Community Join

5 / 278 results

community Hair loss after COVID or vaccination isn’t “made up” but it’s also not what TikTok makes it sound like

2 upvotes 8 months ago

COVID and COVID vaccination can trigger hair loss, primarily telogen effluvium, due to stress and immune system activation. Proper diagnosis and addressing factors like nutrition and stress are crucial for recovery.

community Regrowth with only Nizoral and Lifestyle Changes; focusing on scalp health & nervous system

89 upvotes 7 months ago

The user reported subtle hair regrowth by focusing on scalp health and lifestyle changes, using Nizoral shampoo and methods to reduce inflammation and cortisol, without using finasteride, minoxidil, or other common treatments. Opinions in the conversation varied, with some skeptical of the results and others acknowledging the potential benefits of addressing scalp health and inflammation.

community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System

67 upvotes 11 months ago

PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.

community What Norwood is this guinea pig and what’s bro’s stack?

2174 upvotes 4 months ago

The conversation humorously discusses a guinea pig's hair care routine and its perceived resistance to hair loss, contrasting it with human hair loss treatments like Minoxidil. Users joke about the guinea pig's hair being ideal for transplants and express envy over its fluffy appearance.

community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism

in Research/Science 194 upvotes 1 year ago

Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.

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Learn

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learn Stem Cell Factor

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Baricitinib

JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

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Clinics

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