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Glossary Immune response modifier

substance that alters immune system reactions to threats

An immune response modifier is a substance that can alter the way the immune system reacts to various threats, such as infections or diseases. These modifiers can either boost the immune response to help fight off pathogens or suppress it to reduce inflammation and autoimmunity. For example, in the context of alopecia, certain immune response modifiers might be used to prevent the immune system from attacking hair follicles, thereby reducing hair loss.

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Research

5 / 1000+ results

research Montagna Symposium 2013—Light and Skin: How Light Sustains, Damages, Treats, Images and Modifies Skin Biology

1 citations , July 2014 in “The journal of investigative dermatology/Journal of investigative dermatology”

This review discusses various topics from the 62nd Annual Montagna Symposium on the Biology of Skin, focusing on the diverse effects of light on skin biology, and reports no new clinical results.

research Skin wound healing in humans and mice: Challenges in translational research

276 citations , December 2017 in “Journal of Dermatological Science”

This review discusses the limitations of animal models, particularly mice, in accurately predicting human skin wound healing outcomes and emphasizes understanding species-specific differences in skin characteristics for better translation to clinical settings.

research Study ofDemodexmites: Challenges and Solutions

41 citations , December 2015 in “Journal of the European Academy of Dermatology and Venereology”

This review discusses the challenges and potential solutions in studying Demodex mites and their possible pathogenic role in human skin disorders but reports no new findings.

research Nanoparticle-Based Targeting of Vaccine Compounds to Skin Antigen-Presenting Cells By Hair Follicles and their Transport in Mice

119 citations , December 2008 in “The journal of investigative dermatology/Journal of investigative dermatology”

In this study, transcutaneously applied nanoparticles and viral vectors were shown to penetrate murine hair follicles, internalize in antigen-presenting cells, and induce immune responses, suggesting a promising approach for vaccine delivery.

Autoantigen Discovery in the Hair Loss Disorder, Alopecia Areata: Implications of Post-Translational Modifications

research Autoantigen Discovery in the Hair Loss Disorder, Alopecia Areata: Implication of Post-Translational Modifications

11 citations , June 2022 in “Frontiers in immunology”

This review discusses the challenges in identifying specific hair follicle antigens involved in initiating alopecia areata and highlights the need for further research to understand its etiopathogenesis, reporting no new results.

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Community Join

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community What Are the Technicalities of Curved Hair Transplantation?

4 upvotes 5 months ago

Curved hair transplantation requires specialized tools and techniques to avoid damaging hair follicles, with modified FUE being the preferred method. Proper extraction and implantation angles are crucial to prevent complications like keloids and sterile folliculitis.

community My Theory Of Androgenic Alopecia

16 upvotes 9 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community Rethinking DHT and Hair Loss: Are We Targeting the Wrong Enemy?

in Research/Science 1 year ago

Blocking DHT is not a cure for hair loss; instead, altering how scalp follicles respond to DHT might be more effective. Current treatments like topical finasteride and minoxidil are temporary solutions, and future approaches may involve gene therapy and bioengineering to change follicle behavior.

community Regrowth with only Nizoral and Lifestyle Changes; focusing on scalp health & nervous system

89 upvotes 7 months ago

The user reported subtle hair regrowth by focusing on scalp health and lifestyle changes, using Nizoral shampoo and methods to reduce inflammation and cortisol, without using finasteride, minoxidil, or other common treatments. Opinions in the conversation varied, with some skeptical of the results and others acknowledging the potential benefits of addressing scalp health and inflammation.

community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System

67 upvotes 11 months ago

PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.

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Learn

2 / 801 results

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn procapil

Tried everything and still getting bald patches? Procapil may help calm the immune response Procapil is a cosmetic ingredient complex; laboratory studies of its individual ingredients report anti-inflammatory effects, but no published clinical trial has tested it in alopecia areata or any other immune-related hair loss. Spreading bald patches should be assessed by a dermatologist.

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Clinics

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Hair Systems
Hair Response Inc.Arlington Heights, IL · US

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