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Glossary Immune Function

body's defense mechanism against harmful pathogens and foreign substances

Immune function refers to the body's ability to recognize and defend itself against harmful pathogens like bacteria, viruses, and other foreign substances. It involves a complex network of cells, tissues, and organs, including white blood cells and the lymphatic system, which work together to identify and neutralize threats. For professionals, it encompasses both innate and adaptive immune responses, ensuring both immediate and long-term protection.

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Research

5 / 1000+ results

research The function of BST2 in γδ T Cells, CD8 T Cells, and macrophages in alopecia areata pathogenesis 4231

November 2025 in “The Journal of Immunology”

In this study, researchers observed elevated levels of epidermal γδ T cells, keratinocytes, and an upregulation of the BST2 gene among immune cells in C3H/HeJ mice with alopecia areata, suggesting a potential role in disease pathogenesis.

research Newborn infant skin gene expression: Remarkable differences versus adults

20 citations , October 2021 in “PLoS ONE”

This study found significant differences in gene expression between newborn and adult skin, with infant skin notably increasing processes related to ECM organization, cell adhesion, and collagen fibril organization.

Immune Deficiency-Related Enteropathy-Lymphocytopenia-Alopecia Syndrome Results from Tetratricopeptide Repeat Domain 7A Deficiency

research Immune deficiency–related enteropathy-lymphocytopenia-alopecia syndrome results from tetratricopeptide repeat domain 7A deficiency

64 citations , August 2014 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology”

This study found that biallelic mutations in the TTC7A gene affect lymphocyte and gut epithelial cell function, thereby contributing to the development of inflammatory bowel disease in patients.

research Skin γδ T cell subsets have distinct functions in alopecia areata 3844

November 2025 in “The Journal of Immunology”

This study identified specific genes upregulated in skin γδ T cells involved in alopecia areata, with findings suggesting these cells contribute to disease pathogenesis through inflammatory and Th1 response mechanisms in mouse and possibly human skin.

research Phospholipase A2 in skin biology: new insights from gene-manipulated mice and lipidomics

24 citations , December 2018 in “Inflammation and Regeneration”

This review discusses the roles of various PLA2 enzymes in skin health and disease, highlighting potential pathways for future diagnosis and therapy, but it reports no new clinical results.

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Community Join

5 / 267 results

community How is dht not beneficial to you?

in Finasteride/Dutasteride 111 upvotes 7 months ago

DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.

community Hair loss after COVID or vaccination isn’t “made up” but it’s also not what TikTok makes it sound like

2 upvotes 8 months ago

COVID and COVID vaccination can trigger hair loss, primarily telogen effluvium, due to stress and immune system activation. Proper diagnosis and addressing factors like nutrition and stress are crucial for recovery.

community Rethinking DHT and Hair Loss: Are We Targeting the Wrong Enemy?

in Research/Science 1 year ago

Blocking DHT is not a cure for hair loss; instead, altering how scalp follicles respond to DHT might be more effective. Current treatments like topical finasteride and minoxidil are temporary solutions, and future approaches may involve gene therapy and bioengineering to change follicle behavior.

community How long does it take after an environmental / lifestyle change for hair loss to actually slow down?

5 upvotes 11 months ago

Lifestyle changes may not significantly impact hair loss, as factors like DHT and genetics play a larger role. Some users suggest treatments like finasteride, dutasteride, and microneedling for hair growth.

community Attention Finasteride / Dutasteride and Your liver

374 upvotes 1 year ago

Finasteride may cause elevated liver enzymes, potentially leading to liver issues, though this is rare. Users should monitor liver function and consider topical alternatives if liver sensitivity occurs.

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