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Research

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research Genome-wide association study in alopecia areata implicates both innate and adaptive immunity

717 citations , June 2010 in “Nature”

This study identified key genetic regions associated with alopecia areata, highlighting both acquired and innate immune involvement, with a novel link to the upregulation of ULBP ligands in autoimmune disease.

research Improving human forensics through advances in genetics, genomics and molecular biology

383 citations , February 2011 in “Nature Reviews Genetics”

This review discusses advances in forensic DNA profiling, highlighting new genetic markers and methods for identifying unknown individuals, but reports no new research findings.

research The immunology of the porcine skin and its value as a model for human skin

353 citations , November 2014 in “Molecular immunology”

This review discusses the immune functions of porcine skin and proposes a classification of dendritic cell subsets based on similarities to human skin, but it reports no new clinical results.

research Activating an adaptive immune response from a hydrogel scaffold imparts regenerative wound healing

328 citations , November 2020 in “Nature Materials”

This study found that D-peptide crosslinked MAP hydrogel accelerated material degradation in vivo but significantly enhanced skin regeneration, suggesting an adaptive immune response can drive regenerative healing even with rapid scaffold breakdown.

research Implanted hair follicle stem cells form Schwann cells that support repair of severed peripheral nerves

319 citations , November 2005 in “Proceedings of the National Academy of Sciences”

This study suggests that hair follicle stem cells from transgenic mice can improve nerve regeneration and function, highlighting their potential as an autologous source for regenerative medicine.

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Community Join

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community Im starting to lose porgress is this second shed?

4 upvotes 1 month ago

The conversation discusses hair loss treatments, specifically Minoxidil and Dutasteride, and the experience of a second shedding phase around the 6-month mark. Users share their experiences, noting that shedding is normal and often followed by stronger hair growth.

community Im the first Person in the World that tries 0.2% Alfatrafiol

in Treatment 5 upvotes 5 months ago

The conversation is about a user trying a 0.2% Alfatrafiol treatment for hair loss, combined with Kx826, Minoxidil, microneedling, and ketoconazole. The user reports reduced itching and discusses sourcing the treatment.

community Im struggling with sebderm need help

3 upvotes 6 months ago

The user is struggling with seborrheic dermatitis and plans to try ciclopirox olamine after finding ketoconazole too drying. They are also using finasteride daily.

community Im at the airport right now and have to apply minoxidil

84 upvotes 7 months ago

A person was concerned about applying minoxidil and tretinoin in a public airport bathroom, fearing judgment from others. Most responses reassured them that no one cares, suggesting they apply it in a stall or skip a dose without worry.

community Im looking for a topical to add to my current stack

in Treatment 1 upvotes 1 year ago

The user is considering adding a topical treatment to their current regimen of finasteride and oral minoxidil to protect their temple area, with options like piro, RU58841, or topical finasteride or dutasteride. They are advised against overcomplicating their treatment, but another user suggests a topical with 8% minoxidil/dutasteride for better results.

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Learn

8 / 801 results

learn Niacinamide

How does Niacinamide improve scalp health and reduce hair thinning? Niacinamide improves scalp health by enhancing circulation and reducing inflammation, potentially slowing hair thinning.

learn retinol

How does retinol improve scalp health and prepare the skin for other hair growth treatments? Retinol improves scalp health by promoting cellular turnover and reducing congestion.

learn Clascoterone

Can I use clascoterone if I'm undergoing gender-affirming hormone therapy? No published clinical trial has tested clascoterone in people on gender-affirming hormone therapy, so its safety in that group is unknown. The FDA label reports low systemic exposure and no described effect on blood testosterone, but it also records HPA-axis suppression and raised potassium in a small minority of subjects.

learn Scalp Micropigmentation

Do I need to shave my head for scalp micropigmentation? Shaving your head is generally not required for scalp micropigmentation.

learn Hair Transplant

Can I get a hair transplant if I am completely bald? You can get a hair transplant if donor hair is available, but options may be limited.

learn Rapamycin

mTOR regulator and immunosuppressant used more recently for anti-aging and hair regrowth

learn Baricitinib

JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

learn Metformin

diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

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Experts

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Clinics

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