11 citations
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July 2015 in “Gene” This study found that dihydrotestosterone (DHT) suppresses prostaglandin E2 and TGF-β induced IGF-I gene promoter activity in osteoblasts, suggesting complex interactions among bone growth regulators and potential complications from anabolic steroid use.
July 2026 in “JAAD reviews.” This literature review highlights a potential but uncertain link between GLP-1 receptor agonist therapy for type 2 diabetes and obesity and hair loss, with variations among different medications.
82 citations
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September 2018 in “Nature Communications” This study found that stimulating the olfactory receptor OR2AT4 in human hair follicles with a synthetic sandalwood odorant promotes hair growth ex vivo by decreasing apoptosis and increasing IGF-1 production.
26 citations
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October 1996 in “Journal of Endocrinology/Journal of endocrinology” This study concluded that IGF-I receptors are present on hair follicles and sebaceous glands of cashmere and Angora goats, but melatonin receptors are absent.
25 citations
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December 2008 in “The Journal of Urology” In this study, short-term finasteride treatment reduced apoptotic factors caspase-7 and IGFBP-3 in prostate cancer cells but did not significantly affect androgen receptor expression compared to placebo.