Search

for
Search:

Research

5 / 1000+ results

research Improvement of androgenetic alopecia with topicalSophora flavescensAiton extract, and identification of the two active compounds in the extract that stimulate proliferation of human hair keratinocytes

11 citations , October 2015 in “Clinical and Experimental Dermatology”

This study found that an extract from the root of Sophora flavescens Aiton significantly improved hair growth in patients with androgenetic alopecia over 6 months.

research Establishment of keratinocyte cell lines from human hair follicles

16 citations , September 2018 in “Scientific reports”

This study demonstrates that keratinocyte cell lines derived from cultured hair follicles can fully differentiate in organotypic skin models, offering a minimally invasive alternative to obtaining keratinocytes for research.

research In Vitro Differences Between Keratinocyte Stem Cells and Transit-Amplifying Cells of the Human Hair Follicle

52 citations , October 2005 in “Journal of Investigative Dermatology”

This study found that human hair follicle stem cells formed more colonies and adhered more rapidly, while transit-amplifying cells showed significantly greater mobility.

research 773 Generation of human hair follicle organoids in vitro and ex vivo by co-culture of primary human hair matrix keratinocytes and dermal papilla fibroblasts

June 2020 in “Journal of Investigative Dermatology”

This study observed that human primary adult hair matrix keratinocytes may have the potential to generate hair follicle organoids, suggesting possible applications in hair follicle neogenesis and preclinical hair growth agent screening.

research Morphogenesis of chimeric hair follicles in engineered skin substitutes with human keratinocytes and murine dermal papilla cells

46 citations , August 2012 in “Experimental Dermatology”

In this study, engineered skin substitutes containing murine dermal papilla cells developed hair follicle-like structures when grafted onto mice, suggesting a model for generating chimeric hair.

View more "human hair keratinocytes" in research →

Community Join

5 / 1000+ results

community Weed/THC effects on hair growth/hair loss, and vitality of organ-culture human follicle studies (research review)

4 upvotes 1 year ago

Cannabis and THC may have mixed effects on hair, with some studies suggesting potential negative impacts on hair growth in isolated hair follicles, but these results are hard to apply to living humans. Treatments like minoxidil and finasteride are commonly used for hair loss, and the effects of cannabis might be neutral or vary based on individual factors.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

76 upvotes 2 years ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community Prevention of age-related beard graying in humans by the topical application of Eriodictyon angustifolium extract

5 upvotes 4 years ago

Topical application of Eriodictyon angustifolium extract can prevent and reverse age-related beard graying and darken gray hair by increasing melanin production. Sterubin, a component of the extract, also promotes hair pigmentation and protects cells from DNA damage.

community Minoxidil Response Bottlenecks: Why Sulfation and Transport Matter (And Where Tretinoin Fits In)

in Research 461 upvotes 1 year ago

Minoxidil's effectiveness is limited by the need for sulfation and proper transport to hair follicles, with tretinoin potentially enhancing its effects by promoting enzyme activity and keratinocyte differentiation. Tretinoin may improve minoxidil's response by boosting the expression of necessary enzymes and transporters.

community Short Peptides for Hair Loss: anyone tried any of these?

14 upvotes 5 months ago

Various peptides are discussed for treating male pattern baldness, with some available for topical use like GHK-Cu and Ac-KGHK, while others remain in research stages. Users are interested in experiences and sourcing these treatments.

View more "human hair keratinocytes" in community →

Learn

9 / 800 results

learn Thymosin Beta 4

learn Vitamin D

Vitamin made in the skin from sunlight, also taken as a supplement

learn Melatonin

Hormone that regulates sleep, sold as a supplement

learn Ecklonia Cava

Can Ecklonia Cava reactivate dormant hair follicles and support new growth? No human study has tested whether Ecklonia cava reactivates hair follicles; the evidence comes from cultured cells, cultured follicles and mice.
Can Ecklonia Cava be used as a preventive treatment for early signs of hair thinning? No human trial has tested Ecklonia cava for hair loss, so it cannot be called preventive; the evidence is mouse studies and cell cultures suggesting antioxidant activity and 5-alpha-reductase inhibition in the lab.

learn RU58841

Will I lose my hair if I stop using RU58841? (Spoiler: I might.) There is no published human trial of stopping RU58841; community members commonly report shedding within weeks to months, and androgen biology suggests miniaturization would resume once the topical anti-androgen is withdrawn.

learn Castor oil

Does castor oil make hair grow or is it just a myth? There is no published human trial showing castor oil grows hair. It can make hair look and feel better by reducing breakage and adding shine, which is easily mistaken for growth, and it is not approved anywhere as a hair loss treatment.

learn Redensyl

Does Redensyl prevent hair loss or only help when there's already visible hair loss? The only Redensyl-specific human data is a small, unpublished manufacturer study in men who already had androgenetic alopecia; published trials test multi-ingredient products, and no evidence supports using it to prevent hair loss.

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn KY19382

Experimental compound that activates hair-growth signals, tested only in animals

View more "human hair keratinocytes" in learn →

Clinics

6 / 12 results

All 12 clinic results →

Experts

— no results

Try a deeper search in experts →