learn HMI-115
much-hyped research compound targeting prolactin receptor in scalp
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5 / 10 resultslearn Overview
learn Finasteride
Frontline, gold standard treatment for combatting androgenic alopecia
learn Alfatradiol
a synthetic estrogen used topically as an anti-androgen
learn Pyrilutamide
highly targeted anti-androgen that might have minimal systemic effects
Research
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research Hormonal Regulation and Systemic Signals of Skin Aging
Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.
research Calcineurin/NFATc1 Signaling Links Skin Stem Cell Quiescence to Hormonal Signaling During Pregnancy and Lactation
Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.
research Physiological Regeneration of Skin Appendages and Implications for Regenerative Medicine
The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.
research Hair Follicle Pigmentation: Mechanisms and Factors Influencing Melanin Production
Hair color is determined by melanin produced and transferred in hair follicles.
research The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle
The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.
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5 / 497 resultscommunity New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase
Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.
community Not sure what else to do, can’t use anti-androgens (Baseline Hormonal Bloodwork included) need advice badly
User experienced feminizing side effects from finasteride and tried RU, alfatradiol, and finasteride without success. They are now considering treatments like Stemoxydine, Zix, Minoxidil, Dermarolling, Eucapil, and a hair transplant.
community Do hair follicles ever really "die"? Or does all your front, mid, and crown hair just become vellus?
Hair follicles don't truly die but become severely miniaturized. Treatments like finasteride, dutasteride, and minoxidil can help restore hair by providing nutrients and reducing harmful effects on hair roots.
community Topical melatonin/oral
The conversation discusses the potential positive effects of melatonin on hair growth. The original poster plans to try both oral and topical melatonin and is seeking recommendations for a good source.
community Topical finasteride now the safest possible path?
Topical finasteride is considered a safer option for hair regrowth with fewer systemic side effects compared to oral finasteride. Some users report similar efficacy and side effects between topical and oral treatments, while others prefer topical due to reduced systemic exposure.