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    GlossaryHormone Signaling

    chemical messengers travel through blood to regulate body functions

    Hormone signaling, also known as endocrine signaling, is a process where hormones, which are chemical messengers produced by glands, travel through the bloodstream to target organs or cells. These hormones bind to specific receptors on or inside the target cells, triggering a response that regulates various physiological activities such as growth, metabolism, and reproduction.

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      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties

      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia

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      community GT20029 and PP405 the new fin and min that we been waiting for ?

      in Chat  31 upvotes 2 weeks ago
      PP405 and GT20029 are new hair loss treatments with different mechanisms from traditional options like Minoxidil and Finasteride. PP405 targets hair follicle stem cells to reactivate growth, while GT20029 works as an androgen receptor deleter, both requiring ongoing use for effectiveness.

      community DHT Isn't (Directly) Important

      in Research/Science  101 upvotes 4 months ago
      Finasteride's potential side effects, especially sexual dysfunction, are discussed, with emphasis on hormonal balance between testosterone and estradiol. Users share experiences with finasteride, minoxidil, and dutasteride, highlighting the variability in side effects and the influence of mindset and lifestyle.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  39 upvotes 2 years ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.