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GlossaryHLA-DQ

protein complex involved in immune system antigen presentation

HLA-DQ is a protein complex that plays a crucial role in the immune system by helping the body distinguish between its own cells and foreign invaders. It is part of the human leukocyte antigen (HLA) system, specifically involved in presenting antigens to immune cells, which is essential for initiating an immune response. Variations in HLA-DQ genes are associated with susceptibility to certain autoimmune diseases, including type 1 diabetes and celiac disease.

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research Skin Manifestations of Celiac Disease

132 citations, April 2005 in “Gastroenterology”

A gluten-free diet significantly improves skin and health issues in people with dermatitis herpetiformis, a skin condition linked to celiac disease.

research Discovery of Autoantigens in the Hair Loss Disorder Alopecia Areata: Implications of Posttranslational Modifications

January 2023 in “Karger Kompass. Dermatologie”

Scientists are still unsure what triggers the immune system to attack hair follicles in Alopecia areata.

research Thyroid Diseases and Skin Autoimmunity

24 citations, June 2018 in “Reviews in endocrine and metabolic disorders”

Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.

research Potential Etiological Factors in Frontal Fibrosing Alopecia

January 2022 in “Przegla̧d dermatologiczny”

The exact cause of frontal fibrosing alopecia is unknown, but it's not likely due to sunscreen.

Association of Psoriasis and Psoriatic Arthritis with Human Leukocyte Antigen and Killer Cell Immunoglobulin-Like Receptor Gene Frequency: A Multiethnic Population Study

research Association of Psoriasis and Psoriatic Arthritis with Human Leukocyte Antigen and Killer Cell Immunoglobulin-Like Receptor Gene Frequency: A Multiethnic Population Study

February 2009 in “Journal of The American Academy of Dermatology”

Certain immune system genes are linked to a higher risk of psoriasis and psoriatic arthritis, while others may offer protection.

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