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GlossaryHLA-DQ

protein complex involved in immune system antigen presentation

HLA-DQ is a protein complex that plays a crucial role in the immune system by helping the body distinguish between its own cells and foreign invaders. It is part of the human leukocyte antigen (HLA) system, specifically involved in presenting antigens to immune cells, which is essential for initiating an immune response. Variations in HLA-DQ genes are associated with susceptibility to certain autoimmune diseases, including type 1 diabetes and celiac disease.

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research Skin Manifestations of Celiac Disease

132 citations, April 2005 in “Gastroenterology”

A gluten-free diet significantly improves skin and health issues in people with dermatitis herpetiformis, a skin condition linked to celiac disease.

research Cutaneous Lupus Erythematosus: A Review

149 citations, July 2002 in “Dermatologic clinics”

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

research Cutaneous and Mucosal Manifestations Associated with Celiac Disease

57 citations, June 2018 in “Nutrients”

Celiac disease can cause skin problems that may get better with a gluten-free diet.

research Serological Screening for Coeliac Disease in Vitiligo and Alopecia Areata

46 citations, May 1997 in “British journal of dermatology/British journal of dermatology, Supplement”

Vitiligo is not linked to coeliac disease, but a small number of alopecia areata patients may have it, suggesting they should be tested for coeliac disease.

research Thyroid Diseases and Skin Autoimmunity

24 citations, June 2018 in “Reviews in endocrine and metabolic disorders”

Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.

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