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community Hims topical min/fin spray vs serum

9 upvotes 2 years ago

The conversation is about someone switching from a hair loss treatment spray with alcohol and propylene glycol to a serum with essential oils, questioning the absorption and effectiveness of the new product. The spray and serum both contain 0.3% finasteride and 6% minoxidil.

community Experiencing Scalp Irritation from HIMS Spray/Serum After 6 Months on Fin 0.3/Min 6%

in General 68 upvotes 11 months ago

The user experienced scalp irritation from a Finasteride and Minoxidil spray and serum. They are considering switching to foam, oral treatments, or another provider.

community Update on taking hims spray. I cut my dose to EOD, 2-3 sprays; instead of 4 sprays everyday. Trying to mitigate any leakage of fin into bloodstream.

in Progress Pictures 6 upvotes 3 years ago

A user shared progress pictures and discussed their hair loss treatment, including using Hims spray with finasteride, oral finasteride, castor oil, and derma rolling. They reduced their Hims spray dose to every other day to minimize finasteride absorption into the bloodstream.

community 22M, 5 Months on Hims Min+Fin Spray, Considering Dut+Topical Minox for Thinning

in General 63 upvotes 7 months ago

The user has been experiencing hair loss since age 18 and has tried topical Minoxidil and oral finasteride, which slowed thinning but did not promote regrowth. They are considering switching to Dutasteride with topical Minoxidil after limited success with a Minoxidil and finasteride spray.

community 4 months finasteride + minoxidil combo spray

in Progress Pictures 487 upvotes 1 year ago

The user has been using a finasteride and minoxidil combo spray from Hims for four months, with positive results and no side effects. They apply four sprays nightly, targeting the crown and front of the scalp.

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Research

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research Efficacy and safety of topical finasteride spray solution for male androgenetic alopecia: a phase III, randomized, controlled clinical trial

11 citations , October 2021 in “Journal of The European Academy of Dermatology and Venereology”

This study found that topical finasteride significantly increased hair count in men with androgenetic alopecia compared to placebo while maintaining similar efficacy to oral finasteride but with lower systemic exposure and a reduced impact on serum DHT levels, potentially minimizing sexual side effects.

research Efficacy and safety of topical finasteride spray solution in the treatment of Chinese men with androgenetic alopecia: A phase III, multicenter, randomized, double-blind, placebo-controlled study

March 2025 in “Chinese Medical Journal”

This randomized, double-blind, placebo-controlled phase III trial found that a 24-week treatment with topical finasteride significantly increased hair growth and was well-tolerated in Chinese men with androgenetic alopecia compared to placebo.

research The Pharmacokinetics of Topical Finasteride 0.25% Spray in Chinese Adult Male Volunteers with Androgenic Alopecia: A Phase I Study

February 2025 in “Advances in Therapy”

The topical finasteride spray was safe and well-tolerated with stable effects.

research Topical finasteride 0.25% in HPCH spray for androgenetic alopecia: a single-center retrospective study

July 2026 in “Archives of Dermatological Research”

In this study, topical finasteride showed mild-to-moderate improvement in androgenetic alopecia among a cohort in Saudi Arabia, with combination therapy outperforming monotherapy. Adverse events were rare. The study highlights the need for prospective trials to clarify finasteride's standalone effects.

research Diagnosis Of Occult Asthma By Methacholine Bronchoprovocation Test

August 1986 in “Lung India”

The researchers reported that finasteride prevents further hair loss in males with androgenetic alopecia by promoting hair growth, which helps maintain scalp coverage, but it is not effective for females.

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learn Finasteride

Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically

Finasteride for alopecia: the definitive guide to using it correctly. Finasteride 1 mg daily blocks DHT and, in trials, slowed hair loss in most men over 6 to 12 months, though some men do not respond and the benefit lasts only while the drug is taken. It is prescription-only, carries a pregnancy contraindication, and has reported sexual, mood, breast and semen side effects, some of which men report continuing after stopping.
Does hair strand thickness decrease in men with androgenic alopecia? Can finasteride help restore it? Androgenic alopecia thins hair strands by miniaturizing follicles. The pivotal finasteride trials (1,553 men, 1 mg/day, two years) report increased hair counts and improved assessed appearance, but they measured density, not the diameter of individual strands, so the effect on thickness itself is not established.
Is Finasteride unbeatable or are there equally powerful alternatives? Finasteride has the longest record of trial evidence in male androgenetic alopecia; in pooled 24-week trials dutasteride increased hair counts more, and minoxidil, topical finasteride, PRP, LLLT and microneedling have supporting studies. Regulators warn that finasteride can cause sexual side effects, depression and suicidal thoughts that may persist after stopping, its label also lists breast, semen and other physical effects, and dutasteride now carries a precautionary mood warning; both are prescription-only, and dutasteride and oral minoxidil are off-label for hair loss.

learn Fluridil

How is Fluridil different from other DHT blockers like finasteride? Fluridil is a topical androgen-receptor blocker applied to the scalp, while finasteride is an oral 5-alpha-reductase inhibitor that lowers DHT throughout the body. Finasteride is FDA-approved and far better studied; Fluridil rests on one 43-man trial and is not licensed as a hair-loss medicine, so its long-term safety and effect size are unknown.

learn Saw Palmetto

Is saw palmetto as effective as finasteride against DHT? In the only head-to-head hair study, which was open-label, fewer men improved on saw palmetto (38%) than on finasteride (68%). That study did not measure DHT levels.

learn Dutasteride

5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride

learn Minoxidil

Vasodilator used on the scalp and, at low doses, as a tablet

learn Nanoxidil

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