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research Hair Follicle Dermal Stem Cells and Skin-Derived Precursor Cells: Exciting Tools for Endogenous and Exogenous Therapies

30 citations , April 2017 in “Experimental Dermatology”

Hair follicle stem cells and skin cells show promise for hair and skin therapies but need more research for clinical use.

research The Adenosine-Generating Ecto-Enzyme CD73 Regulates Human Hair Growth

August 2016 in “Journal of Investigative Dermatology”

The enzyme CD73 helps control human hair growth and could be targeted to treat hair growth disorders.

Plasticity and Cytokinetic Dynamics of the Hair Follicle Mesenchyme During the Hair Growth Cycle: Implications for Growth Control and Hair Follicle Transformations

research Plasticity and Cytokinetic Dynamics of the Hair Follicle Mesenchyme During the Hair Growth Cycle: Implications for Growth Control and Hair Follicle Transformations

54 citations , June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings”

Disruptions in hair follicle fibroblast dynamics can cause hair growth problems.

research 17β-Estradiol May Control Human Hair Follicle Growth Also via Up-Regulating the Expression of Cannabinoid Receptor Type 1

April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

17β-estradiol may help hair growth by increasing cannabinoid receptor type 1.

research Plasticity and Cytokinetic Dynamics of the Hair Follicle Mesenchyme: Implications for Hair Growth Control

158 citations , May 2003 in “Journal of Investigative Dermatology”

Hair growth is influenced by dynamic changes in hair follicle cells, which could help treat hair loss.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community TWIST-1 and the cure: Is it really that easy?

in Research/Science 283 upvotes 3 years ago

TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 41 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Tazarotene shows strong standalone hair regrowth potential, not just a Minoxidil enhancer. Backed by VEGF, HF regeneration, and angiogenesis pathways. Here’s why.

in Research/Science 137 upvotes 4 months ago

Tazarotene shows potential as a standalone treatment for hair regrowth by stimulating new hair follicle formation and promoting angiogenesis, similar to microneedling effects. It can be used topically without minoxidil, but users should start with a low concentration to avoid irritation.

community Minoxidil actually reduces wrinkles

in Research/Science 209 upvotes 11 months ago

Minoxidil may improve or worsen skin quality, with topical forms causing dryness and wrinkles, possibly due to alcohol content, while oral forms have fewer side effects. Some users consider using tretinoin to mitigate negative effects.

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