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Genetic Ablation of Myelin Protein Zero-Like 3 in Mice Increases Energy Expenditure, Improves Glycemic Control, and Reduces Hepatic Lipid Synthesis

research Genetic Ablation of Myelin Protein Zero-Like 3 in Mice Increases Energy Expenditure, Improves Glycemic Control, and Reduces Hepatic Lipid Synthesis

14 citations , May 2013 in “American Journal of Physiology-endocrinology and Metabolism”

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

research Rodent Models in Placental Research: Implications for Fetal Origins of Adult Disease

7 citations , January 2022 in “Animal Reproduction”

Using rodents for research shows that health problems in the womb can cause diseases later in life.

research The Interplay Between Finasteride-Induced Androgen Imbalance, Endoplasmic Reticulum Stress, Oxidative Stress, and Liver Disorders in Paternal and Filial Generation

October 2022 in “Biomedicines”

Finasteride in male rats causes liver and metabolic issues in their offspring.

research Health Risks Associated with Long-Term Finasteride and Dutasteride Use: It's Time to Sound the Alarm

17 citations , January 2020 in “The World Journal of Men's Health”

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

research Bioconversion, Pharmacokinetics, and Therapeutic Mechanisms of Ginsenoside Compound K and Its Analogues for Treating Metabolic Diseases

11 citations , March 2024 in “Current Issues in Molecular Biology”

Ginsenoside compound K shows promise for treating metabolic diseases like diabetes and obesity.

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community Having androgen receptor density and sensitivity at wrong f*ing place

in Satire 7 upvotes 1 year ago

The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.

community A warning to those using or thinking about using Dutasteride – Follow-up

in Finasteride/Dutasteride 17 upvotes 4 years ago

The post and conversation are about the long-term side effects of using Dutasteride and Finasteride for hair loss, including issues like raised liver enzymes, high cholesterol, and loss of libido. The user advises regular blood work and careful monitoring for those using these treatments.

community Could fatty liver(other issues related to it..)play a role in Dupa/Aga?

in Treatment 6 upvotes 1 year ago

Fatty liver and related issues may influence hair loss conditions like Dupa/Aga. Treatments discussed include Minoxidil, finasteride, RU58841, myo-inositol, and L-glutamine.

community How much would a high dose dutasteride scalp dht inhibition be?

in Finasteride/Dutasteride 10 upvotes 1 year ago

The conversation discusses the potential for high doses of dutasteride to completely inhibit scalp DHT and speculates whether this could cure baldness when combined with a topical antiandrogen. Specific dosages mentioned are 0.5 mg reducing scalp DHT by 55% and 2.5 mg by about 79%.

community Oral minoxidl - Is this a medication that's generally safe to take for life? Like what I understand oral fin is? Also do studies show that in general or in a significant amount of more cases that results with oral minox + oral fin > oral fin in terms of long-term use(talkin 20+ years).

in Minoxidil 77 upvotes 10 months ago

Oral minoxidil combined with finasteride can improve hair density, but long-term safety is uncertain due to potential side effects like heart and kidney issues. Users report mixed experiences, with some experiencing side effects and others finding it effective for hair maintenance.

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