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Research

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research Heat‐damaged evaluation of virgin hair

13 citations , March 2019 in “Journal of cosmetic dermatology”

This study found that thermal hair-straightening devices significantly damaged the cuticle and cortex of virgin Asian and Caucasian hair, with Asian hair experiencing more protein loss than Caucasian hair.

Thermal Damage, Styling Product Overuse, and Heat Protection Strategies in Professional Hairstyling: An Expert-Based Protocol for Hair Structure Preservation

research Thermal Damage, Styling Product Overuse, and Heat Protection Strategies in Professional Hairstyling: An Expert-Based Protocol for Hair Structure Preservation

February 2026 in “Zenodo (CERN European Organization for Nuclear Research)”

This study analyzed how professional hairstyling practices cause thermal damage to human hair, focusing on heat exposure and product use, and proposed a protocol for minimizing damage with heat protection strategies and optimal temperature recommendations.

research Thermal Damage, Styling Product Overuse, and Heat Protection Strategies in Professional Hairstyling: An Expert-Based Protocol for Hair Structure Preservation

February 2026 in “Zenodo (CERN European Organization for Nuclear Research)”

The study analyzed how professional hairstyling practices, such as excessive heat and product use, cause thermal damage to hair, and it proposed a protocol that includes heat protection strategies and optimal temperature ranges to minimize this damage for hairstylists.

research Establishment of Heat‐Damaged Model for Hair

July 2025 in “Journal of Cosmetic Dermatology”

This study established a model of heat-damaged hair to assess hair care products, finding that daily hair drying for a month causes notable cuticle lifting, reduced mechanical properties, and increased protein release, and the model simulates even more severe damage.

research Application of single hair fibre tensile measurements to create an industry‐standard heat damage scale for hair

July 2025 in “International Journal of Cosmetic Science”

In this study, researchers developed a new 6-point scale for evaluating heat damage to hair from straighteners, finding a strong correlation between technical damage measurements and human perception of hair damage.

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Community Join

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community due to medication, age, over use of color and heat, my hair began to fall out and break. I shaved my head (35F) and I’m horrified at myself now

in Female 46 upvotes 1 year ago

A woman experienced significant hair loss due to medication, hair coloring, and heat damage, leading her to shave her head and feel distressed. She is considering using wigs and possibly oral minoxidil to manage the situation while her hair regrows.

community Aminexil. Where to get it?

4 upvotes 7 years ago

The conversation discusses transitioning from topical to oral minoxidil for hair loss treatment and explores the potential use of Aminexil, despite concerns about its effectiveness compared to minoxidil. It highlights the risks and side effects of oral minoxidil, such as potential heart and liver damage, and emphasizes the importance of monitoring blood pressure.

community Can topical Minoxidil use backfire if you’re a non-responder?

1 upvotes 3 months ago

The user has been using finasteride successfully to stop hair shedding and is considering using topical minoxidil for regrowth but is concerned about being a non-responder and potential negative effects. They are cautious about using oral minoxidil due to past heart issues and are exploring other methods like tretinoin cream and dermarolling, though they worry about possible skin damage.

community Does microneedling damage scalp?

in Research/Science 12 upvotes 2 years ago

Microneedling does not prevent future hair transplants, but some surgeons report the skin becomes "harder" in treated areas. There is no clear evidence to confirm this effect.

community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System

67 upvotes 11 months ago

PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.

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Learn

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learn Stem Cell Factor

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn GHK-Cu

Heard alopecia areata leaves scar-like spots? Some peptides are helping those areas regrow hair. Alopecia areata patches usually still have living follicles. Peptides are being studied as a possible add-on, but the evidence is small and early. See a dermatologist for treatment.

learn capsicum

Can the heat from capsicum actually wake up dormant hair follicles? Capsicum heat may stimulate dormant hair follicles through increased blood flow and growth factors.

learn Minoxidil

What are the side effects of minoxidil, and can oral minoxidil affect your heart? Minoxidil can cause side effects, and because it was designed as a blood-pressure drug, some of them involve the heart and circulation. Published studies of low-dose oral minoxidil describe mostly mild problems, but fluid around the heart, pericarditis and other serious events have been reported, and the long-term picture is still being studied. Do not start, stop or change minoxidil without a doctor, and if you develop chest pain, a racing heartbeat, shortness of breath, fainting, swelling or rapid weight gain while using it, stop and seek medical care.

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Clinics

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