January 2013 in “Tampere University Institutional Repository (Tampere University)”
This study observed that Tudor-SN protein may play a significant role in the immune system and that polyamines can influence hairgrowth in a mousemodel.
11 citations
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September 2012 in “Journal of Nanjing Medical University”
In this study, cyclosporine A stimulated hairgrowth in mouse vibrissae organ culture by promoting matrix cell proliferation and altering growth factor expression.
This study found that cyclosporine A stimulates hairgrowth in a mousemodel by preventing catagen development and increasing expression of certain growth factors.
9 citations
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July 2021 in “Journal of Medicinal Food”
This study found that consuming Lactobacillus paracasei HY7015 promoted hairgrowth and follicle maturation in mice, likely through stimulating dermal papilla cell proliferation and growth factor secretion.
Adipose-derived stem cells with ATP improved hair regrowth in male and female mice with androgenetic alopecia. The most effective treatments were low dose stem cells with ATP for males and medium dose stem cells with non-liposomal ATP for females.
2-deoxy-D-ribose, a sugar molecule, is found to be 80%-90% as effective as Minoxidil in promoting hairgrowth, showing potential for alopecia treatment. Concerns include high cost, lack of human studies, and possible side effects like diarrhea and nausea.
Pilose antler extracts may promote hairgrowth in androgenetic alopecia by activating hair follicle stem cells through the AKT and Wnt pathways. However, results in mice may not directly apply to humans due to differences in genetic and biochemical conditions.
Hairgrowth relies on mechanical forces, not just chemicals, with tissue acting like a motor. Minoxidil and finasteride help, but maintaining tissue elasticity and addressing mechanical issues are essential.
What is Platelet-Derived Growth Factor Beta Polypeptide, and how does it help stimulate new hairgrowth?PDGF-BB is a growth factor that signals to dermal papilla cells and promotes blood-vessel formation; mouse studies report it can push follicles into the growth phase, and human evidence comes only indirectly from PRP trials. No PDGF product is approved for hair restoration and there is no published human trial of PDGF-BB on its own.
Which is more effective: peppermint essential oil or extract in shampoo?Neither form has been tested for hair loss in people. Peppermint essential oil is the only one with any experimental support — a single four-week mouse study in which 3% peppermint oil outperformed 3% minoxidil on follicle counts — while peppermint extract in shampoo is a low-concentration cosmetic ingredient with no hair-growth data.