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research The Human Papillomavirus Type 11 Upstream Regulatory Region Triggers Hair-Follicle-Specific Gene Expression in Transgenic Mice

9 citations , June 1999 in “Journal of Investigative Dermatology”

This study observed hair-specific transcription of a reporter gene in transgenic mice, with increased expression after dexamethasone and ultraviolet B treatment.

research The Enrichment of Specific Hair Follicle-Associated Cell Populations in Plucked Hairs Offers an Opportunity to Study Gene Expression Underlying Hair Traits

2 citations , December 2022 in “International journal of molecular sciences”

This study compared RNA-seq results from horse plucked-hair and skin-biopsy samples, finding that plucked hairs were enriched with hair-follicle keratinocytes, while biopsies showed enrichment for other cell types.

research Time-course RNA-seq analysis reveals stage-specific and melatonin-triggered gene expression patterns during the hair follicle growth cycle in Capra hircus

9 citations , February 2022 in “BMC Genomics”

This study examined gene expression in cashmere goats and identified key pathways and molecular regulators that influence hair follicle growth stages and melatonin's role in promoting cashmere growth.

research Additional file 10 of Time-course RNA-seq analysis reveals stage-specific and melatonin-triggered gene expression patterns during the hair follicle growth cycle in Capra hircus

January 2022 in “Figshare”

Melatonin affects specific gene patterns and biological processes in goat hair growth.

research Additional file 2 of Time-course RNA-seq analysis reveals stage-specific and melatonin-triggered gene expression patterns during the hair follicle growth cycle in Capra hircus

January 2022 in “Figshare”

Melatonin affects when and how goat hair follicle genes turn on and off during growth cycles.

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Community Join

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community It’s all about the stem cells…

53 upvotes 4 years ago

Hair loss is linked to the loss of stem cells in hair follicles, and potential treatments include gene editing and microneedling. Discussions also mention using Minoxidil, finasteride, and dermarolling to improve hair growth.

community Minoxidil Response Bottlenecks: Why Sulfation and Transport Matter (And Where Tretinoin Fits In)

in Research 461 upvotes 1 year ago

Minoxidil's effectiveness is limited by the need for sulfation and proper transport to hair follicles, with tretinoin potentially enhancing its effects by promoting enzyme activity and keratinocyte differentiation. Tretinoin may improve minoxidil's response by boosting the expression of necessary enzymes and transporters.

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Learn

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learn Hair Transplant

Surgery that moves hair follicles from the back of the scalp to thinning areas

learn Sulforaphane

How often should sulforaphane-based products be used for hair loss prevention? No human trial has tested sulforaphane for hair loss prevention, so there is no established usage frequency. Oral supplements are taken daily in research on unrelated conditions and the hair-specific evidence is limited to cell, mouse and isolated-follicle studies, so any schedule is extrapolation rather than a dosing guideline.

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Adenosine

Molecule the body uses for energy, used as a cosmetic hair-lotion ingredient

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SMP Specialist
Hairo Fallas
Newark, NJ, United States