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research MULTIPLE DEFECTS OF THE HAIR SHAFT IN NETHERTON'S DISEASE.

58 citations , November 1969 in “British Journal of Dermatology”

This report describes two patients with ichthyosis linearis circumflexa exhibiting symptoms resembling Netherton's disease, noting multiple hair shaft defects and discussing a possible connection to aminoaciduria.

research Neurotrichosis: Hair‐shaft Abnormalities associated with Neurological Diseases

33 citations , December 1982 in “Developmental Medicine & Child Neurology”

The authors reviewed cases of six children with both hair-shaft abnormalities and neurological disorders, noting that such hair defects may indicate neurological conditions, including potentially treatable metabolic errors.

research HAIR AND SYSTEMATIC DISEASE

58 citations , October 2001 in “Dermatologic Clinics”

This review discusses the categorization of hair loss and increased hair density disorders related to systemic diseases and reports no clinical results, emphasizing the potential diagnostic value of history, physical examination, and histopathologic data.

research Investigation of hair shaft in seborrheic dermatitis using atomic force microscopy

17 citations , January 2011 in “Skin Research and Technology”

Hair from people with seborrheic dermatitis is thicker scaled, more damaged, and thinner than healthy hair, and atomic force microscopy can help monitor the condition.

research Diseases of the Hair and Scalp

July 1994 in “Archives of Dermatology”

This book reviews the biology and clinical assessment of both normal and abnormal hair growth, providing a detailed examination of various hair and scalp diseases but reports no new research findings.

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community Hair Loss “Cure” for Inflammation: Topical Roflumilast

in Research/Science 32 upvotes 8 months ago

Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.

community The new growth in hair loss research: With increasing evidence of its impact on mental health, scientists are pushing forward with breakthroughs on balding. Later this year, scientists will launch one of the first ever clinical trials with hair follicles grown entirely from stem cells.

324 upvotes 7 years ago

Hair loss impacts mental health, with treatments like Minoxidil, finasteride, and stem cell transplants discussed. There is hope for future breakthroughs, but current treatments are limited, and awareness is lacking.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Exosomes

Microscopic delivery system that sends growth-promoting signals to hair follicles

learn Vascular Endothelial Growth Factor

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Thymosin Beta 4

learn Cetirizine

How does cetirizine reduce inflammation linked to hair loss? Cetirizine is proposed to lower prostaglandin D2 and raise prostaglandin E2 around hair follicles; three small trials of a compounded 1% topical report modest increases in hair density and shaft thickness, with minoxidil doing better head-to-head. Topical cetirizine is off-label and unapproved for hair loss, and the evidence is too thin to call it effective or safe.

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SMP Specialist
Hairo Fallas
Newark, NJ, United States