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research Validation of hair estradiol immuno-assays across the menstrual cycle in emerging adults

February 2019 in “Psychoneuroendocrinology”

This study suggests that measuring hair DHEA and testosterone can reliably reflect long-term average hormone levels in women, overcoming daily and menstrual fluctuations seen in salivary hormone assessments.

research Dissecting hair breakage in alopecia areata: the central role of dysregulated cysteine homeostasis

3 citations , May 2024 in “Amino Acids”

This review identifies cysteine's central role in hair growth and its potential impact on Alopecia Areata's pathogenesis, suggesting examination of cysteine metabolism might clarify the disease's underlying mechanisms and lead to new treatments.

research Qiviut cortisol reflects hypothalamic–pituitary–adrenal axis activity in muskoxen (Ovibos moschatus)

7 citations , May 2021 in “General and comparative endocrinology”

This study concluded that qiviut cortisol can be used as a measure of HPA axis activity in muskoxen, with hair growth phase and body region affecting cortisol levels.

research Segmental hair analysis as a retrospective testosterone diary: possibilities and pitfalls

September 2023 in “Scientific reports”

This study observed that testosterone concentrations in hair segments show some stability over time, but are influenced by factors like sebum integration, hair washing frequency, and individual hair growth rates.

research (053) Multidisciplinary Treatment of Transgender Woman with Severe Gender Dysphoria and Comorbid Psychiatric Disorders - Case Report

June 2023 in “The journal of sexual medicine”

This case report describes a 10-year multidisciplinary treatment of a transgender woman in Slovenia, reporting a successful medical and social transition with stable emotional health, abstinence from alcohol, and no regrets following her transition.

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Community Join

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community Dutasteride mesotherapy doesn’t impact your bodies serum hormone levels?

2 upvotes 1 year ago

Dutasteride mesotherapy may stabilize hair loss and improve hair without significantly affecting serum DHT levels, but it can still have systemic effects. Users discuss using topical and oral dutasteride, with some experiencing side effects and considering hair transplants.

community No hair loss progress in 11 years. Why did my baldness stop?

21 upvotes 6 days ago

Hair loss can stop or slow down unpredictably, often due to genetic factors and hormone sensitivity. Some individuals experience early hairline changes that stabilize without treatment.

community Has anyone stabilized their hair loss on fin and then switched to RU?

4 upvotes 6 months ago

The conversation discusses switching from oral finasteride to topical RU58841 for hair loss, with concerns about hormonal effects and libido. Some users suggest alternatives like dutasteride, while others share mixed experiences with RU58841's effectiveness.

community : 3-Year Transformation: How adding an LLLT Cap finally stabilized my 200+ hair/day shed (Fin/Min/Niz/LLLT)

322 upvotes 4 months ago

Adding an LLLT laser cap to a routine of finasteride, minoxidil, and ketoconazole shampoo significantly reduced hair shedding from 200+ hairs a day to around 80, improving scalp health. The user attributes the laser cap as the key factor in stabilizing hair loss after two years of using other treatments.

community 2.5mg Dut/RU/minoxidil can't counter 15mg Testosterone..

in Finasteride/Dutasteride 6 upvotes 1 year ago

Despite using Dutasteride, RU58841, and Minoxidil, hair loss continues due to low testosterone levels from taking 15mg of testosterone weekly, which may not produce enough estrogen. Increasing testosterone dosage and stabilizing hormone levels might help address the issue.

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Learn

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learn Estradiol

Estrogen hormone, prescribed in tablet, patch and gel forms

Why is Estradiol used to treat hair loss in women and transgender people undergoing hormone therapy? Estradiol is used within supervised hormone therapy and may slow hormone-related hair loss in some women and trans women, but the evidence is limited and it carries serious whole-body risks.
Is applying Estradiol directly to the scalp effective for hormone-related hair thinning? There are no good-quality trials showing that estradiol applied to the scalp treats hormone-related thinning. Skin-applied estradiol can still enter the bloodstream and pass to others through contact.

learn Neem Oil

Oil from the neem tree, used in traditional remedies

learn Adenosine

Adenosine : Can it help if my hair loss is due to a hormonal imbalance like PCOS or DHT? Adenosine does not act on hormones, and it has not been studied in PCOS. Small trials in pattern hair loss showed thicker hairs.

learn Alfatradiol

Alfatradiol: What does a form of estrogen have to do with hair loss in men? Alfatradiol (17α-estradiol) is a topical hormone sold without prescription in German pharmacies, licensed there for mild androgenetic alopecia, and not FDA-approved. The controlled trial evidence is in women, where hair density and thickness stayed nearly unchanged over 6 months while minoxidil improved them (the trial had no placebo group); no comparable placebo-controlled trial in men appears to have been published.

learn sh-Polypeptide-7

Does sh-Polypeptide-7 stimulate hair follicles or reduce scalp inflammation? sh-Polypeptide-7 is the INCI name for a lab-made form of human growth hormone (somatotropin) — not EGF, which is sh-Oligopeptide-1. Growth hormone and IGF-1 signalling is documented in hair follicle biology, but there is no published human trial of sh-Polypeptide-7 applied to the scalp for hair growth or scalp inflammation.

learn Hair Transplant

Surgery that moves hair follicles from the back of the scalp to thinning areas

learn Melatonin

Hormone that regulates sleep, sold as a supplement

learn Caffeine

Stimulant used in hair shampoos and lotions

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