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research A rare case of chronic genian fistula with oral mucosal hair follicle inclusion: case report and review of the literature

November 2025 in “Frontiers in Oral Health”

This case study highlights the novel occurrence of a genian fistula with intraoral hair follicle inclusion in a patient without prior facial surgery, emphasizing the need for a comprehensive approach combining clinical, radiologic, and histopathologic analysis for accurate diagnosis and management.

research Extracellular Vesicles Including Exosomes for Hair Follicle Regeneration

2 citations , January 2022 in “Stem cell biology and regenerative medicine”

This review discusses the potential of extracellular vesicles from various sources as promising candidates for hair growth stimulation but notes that clinical trials are needed to confirm their effectiveness and safety.

research Developing a Device for Collecting of Hair Follicles for Non-incision Hair Transplantation

October 2018

The researchers developed a new follicular unit extraction system with adjustable needle lengths and precise rotation speed, which they report as being superior to existing systems for non-incisional hair transplants.

research Mitotic processes in hair follicles and the morphostructure of sheep skin upon inclusion of a water-soluble fatty acid complex into their diets

April 2025 in “Ukrainian Journal of Veterinary and Agricultural Sciences”

This study observed that feeding ewes a water-soluble complex of fatty acids increased primary hair follicle bulb diameter and mitotic activity, suggesting a positive correlation with wool growth.

research A Novel Epithelial Keratin, hK6irs1, is Expressed Differentially in All Layers of the Inner Root Sheath, Including Specialized Huxley Cells (Flügelzellen) of the Human Hair Follicle

86 citations , May 2002 in “Journal of Investigative Dermatology”

This study characterized a new human keratin, hK6irs1, specifically found in the inner root sheath of hair follicles, which suggests its role in the structural integrity and guidance of growing hair shafts.

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Community Join

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community Fully Functional Hair Follicles Have Been Grown in The Lab For The First Time

375 upvotes 6 months ago

Scientists have successfully grown functional hair follicles in the lab, marking a significant advancement in hair regeneration research. A user shared their personal experience with hair loss treatments, including Minoxidil and Finasteride, and plans to share a detailed protocol for hair restoration.

community My follicles are getting ready to throw in the towel 😮‍💨

448 upvotes 7 months ago

The conversation humorously discusses hair loss treatments, including Minoxidil, finasteride, and RU58841, and debates the merits of being bald versus using hair systems. Opinions vary on confidence and attractiveness related to baldness and hair systems.

community Do mens shampoo for hair loss help with balding?

in Research/Science 44 upvotes 10 months ago

Shampoos, including those with ketoconazole, may offer mild benefits for hair health but are not effective for stopping hair loss or balding. Effective treatments for hair loss include finasteride and minoxidil, often used together, while shampoos are generally not on the scalp long enough to impact hair follicles significantly.

community What are the upcoming or promising future developments in hair loss?

31 upvotes 2 years ago

The conversation discusses potential future hair loss treatments, including SCUBE3, hair follicle cloning, and GT20029, with mentions of past disappointments like CosmeRNA and hopes for treatments like Verteporfin for infinite donor hair.

community MY Hair Loss Treatment Summary

9 upvotes 2 years ago

The conversation is about various hair loss treatments, including finasteride, minoxidil, RU58841, and natural supplements like saw palmetto and pumpkin seed oil. It also covers methods to improve blood circulation, nourish hair follicles, and address underlying health issues like vitamin D deficiency and high cortisol levels.

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Learn

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learn Hair Transplant

Is a hair transplant painful? Clinics say local anaesthetic makes the procedure itself mostly comfortable, but the anaesthetic injections sting and soreness for a few days afterwards is common. Pain varies from person to person.

learn zinc PCA

What does zinc do in hair follicles, and does low zinc affect hair loss? Zinc is needed for cell growth, including in hair follicles, and studies link low blood zinc with some types of hair loss. Zinc supplements have been tested only in small studies of people who were low in zinc.

learn Scalp Micropigmentation

scalp tattoos to mimic the appearance of light stubble

What is Scalp Micropigmentation and how does it help people with visible hair loss? Scalp Micropigmentation creates the illusion of hair follicles on the scalp for visible hair loss.

learn SCUBE3

Can SCUBE3 help people with androgenetic alopecia, or is it meant for other types of hair loss? SCUBE3 has been studied only in mice, including one donor's human follicles grafted onto mice. It has not been tested in people with androgenetic alopecia or any other type of hair loss.

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Peppermint

herb and oil thought to stimulate skin and hair

learn Vitamin D

Vitamin made in the skin from sunlight, also taken as a supplement

learn PP405

mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

learn Niacinamide

Does niacinamide support hair follicle nutrition? Niacinamide is a precursor of NAD+, a molecule cells use for energy. Whether it affects hair follicles in people has not been tested.

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Clinics

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Experts

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SMP Specialist
Hairo Fallas
Newark, NJ, United States

Hairo Fallas