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GlossaryHematopoietic Stem Cells

produce all types of blood cells in bone marrow

Hematopoietic Stem Cells (HSCs) are a type of stem cell found in the bone marrow that are responsible for producing all the different types of blood cells, including red blood cells, white blood cells, and platelets. These cells have the unique ability to both self-renew, creating more HSCs, and differentiate into various specialized blood cells, making them crucial for maintaining a healthy and functional blood system.

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ZO-1 Boosts the In Vitro Self-Renewal of Pre-Haematopoietic Stem Cells from OCT4-Reprogrammed Human Hair Follicle Mesenchymal Stem Cells Through Cytoskeleton Remodeling

research ZO-1 Boosts the In Vitro Self-Renewal of Pre-Haematopoietic Stem Cells from OCT4-Reprogrammed Human Hair Follicle Mesenchymal Stem Cells Through Cytoskeleton Remodeling

December 2024 in “Stem Cell Research & Therapy”

ZO-1 helps hair follicle stem cells renew better by changing their structure.

research Characterization of CD4+ Stem Cells of the Skin and Their Role in Skin Homeostasis and Tumorigenesis

1 citations, January 2021

CD4+ skin cells may be precursors to basal cell carcinoma.

research A Review of the Impact of Calorie Restriction on Stem Cell Potency

4 citations, August 2021 in “The Malaysian journal of medical sciences/The Malaysian Journal of Medical Science”

Eating fewer calories improves the ability of stem cells to repair and renew the body in various tissues.

research Hair Follicle Dermal Cells Support Expansion of Murine and Human Embryonic and Induced Pluripotent Stem Cells and Promote Hematopoiesis in Mouse Cultures

3 citations, August 2018 in “Stem cells international”

Hair follicle cells help maintain and support stem cells and blood cell formation.

research Stretching the Limits: From Homeostasis to Stem Cell Plasticity in Wound Healing and Cancer

124 citations, February 2018 in “Nature Reviews Genetics”

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

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community Painkillers May Block Minoxidil

in Research/Science 14 upvotes 4 months ago

Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.