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    Glossary Multipotent

    stem cells that can develop into several related cell types

    Multipotent refers to a type of stem cell that has the ability to develop into multiple, but limited, cell types within a particular tissue or organ. For example, hematopoietic stem cells in the bone marrow are multipotent because they can differentiate into various types of blood cells, but not into cells of other tissues like neurons or muscle cells. This characteristic makes them crucial for tissue repair and regeneration in specific areas of the body.

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    1. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001 · 949 citations
    2. Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin Genes & Development · 2001 · 555 citations
    3. Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epidermis Cell stem cell · 2009 · 503 citations
    4. Multipotent nestin-positive, keratin-negative hair-follicle bulge stem cells can form neurons Proceedings of the National Academy of Sciences · 2005 · 419 citations
    5. Isolation of a Novel Population of Multipotent Adult Stem Cells from Human Hair Follicles American Journal Of Pathology · 2006 · 344 citations
    6. Multipotent hair follicle stem cells promote repair of spinal cord injury and recovery of walking function Cell Cycle · 2008 · 144 citations
    7. Microenvironmental reprogramming of thymic epithelial cells to skin multipotent stem cells Nature · 2010 · 116 citations
    8. Multi-layered environmental regulation on the homeostasis of stem cells: The saga of hair growth and alopecia Journal of Dermatological Science · 2012 · 59 citations
    9. Generation and Characterization of Multipotent Stem Cells from Established Dermal Cultures PLoS ONE · 2012 · 58 citations
    10. Maintenance of high proliferation and multipotent potential of human hair follicle-derived mesenchymal stem cells by growth factors International Journal of Molecular Medicine · 2013 · 56 citations
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