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research Kopexil vs minoxidil: In vivo comparative study on hair growth, hair growth promoting factors and toxicity

August 2024 in “Bioimpacts”

In this study on mice, a hydro-alcoholic solution containing kopexil significantly enhanced hair growth and increased hair-promoting factors without causing notable liver or kidney toxicity compared to minoxidil.

research Therapeutic efficacy and safety of a 1927-nm fractionated thulium laser on pattern hair loss: an evaluator-blinded, split-scalp study

21 citations , January 2018 in “Lasers in Medical Science”

This study concluded that 12 sessions of fractionated thulium laser treatment improved hair density and thickness in patients with pattern hair loss, with further benefits from adding a growth factor solution post-treatment.

research Transdermal delivery of a new hair growth promoting solution in patients with hair loss

2 citations , January 2019 in “International Journal of Case Reports and Images”

This article discusses treatments for male pattern alopecia, noting variable response rates, but reports no new clinical results.

research The role of mimicking growth factors to control anagen phase: Evaluation in vitro and in vivo

February 2010 in “Journal of The American Academy of Dermatology”

Mimicking growth factors in a topical solution can prolong hair growth phase and reduce hair loss without side effects.

research Phyllanthus emblica Extract-loaded Transfersomes for Hair Follicle Targeting: Phytoconstituents, Characterization, and Hair Growth Promotion

1 citations , January 2022 in “Journal of Oleo Science”

This study found that an aqueous extract of Phyllanthus emblica, primarily containing gallic acid, can activate hair growth gene expression and is effectively delivered to hair follicles using transfersomes.

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community Effectiveness and Safety of Hair Growth Formulation Containing Tectona grandis L.f (Teak) Leaf Extract

in Chat 33 upvotes 1 year ago

Teak leaf extract shows potential as a mild hair growth promoter for androgenic alopecia, with similar positive trends to minoxidil but without significant side effects. It can be made at home using dried teak leaves and ethanol, though its effectiveness compared to other treatments like finasteride is debated.

community Is Ketoconazole a big factor in preventing hairloss?

in Ketoconazole 41 upvotes 1 year ago

Ketoconazole shampoo may help with scalp health and inflammation but is not a substitute for DHT blockers like finasteride. It is generally considered a minor addition to hair loss treatment, with varying opinions on its effectiveness.

community Is DHT actually the cause of male pattern hair loss or just a correlating factor? Why I think the research is more complicated than we're told and why I've been looking into GHK-Cu

78 upvotes 4 months ago

DHT is not the only cause of male pattern hair loss; genetic sensitivity, inflammation, and fibrosis also contribute. GHK-Cu, a copper peptide, is being explored as an alternative treatment to finasteride and minoxidil, showing potential in improving follicle health.

community Has anyone tried Exosomes from Musely or somewhere else?

10 upvotes 1 year ago

Exosomes from Musely are being discussed as a topical hair loss treatment containing ingredients like latanoprost, caffeine, cetirizine, melatonin, vitamin D3, vitamin E, and biotin. Users are curious about its effectiveness and potential side effects, noting it may take 4-6 months to see results.

community do any supplements actually work?

6 upvotes 2 years ago

A user asked if collagen or hair growth supplements made their hair thicker. Another user suggested that Vitamin D might help if deficient.

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Learn

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learn Mesotherapy

Injections of drug or vitamin mixtures into the scalp

learn Follistatin

Protein that blocks activin, a growth-regulating signal

learn Epidermal Growth Factor

learn Vascular Endothelial Growth Factor

What is Vascular Endothelial Growth Factor (VEGF), and how does it support hair growth in alopecia? In mice, VEGF supports hair growth by increasing blood vessels around follicles. There is no direct evidence that raising VEGF treats hair loss in people.
Can products that stimulate Vascular Endothelial Growth Factor (VEGF) improve blood flow to hair follicles? Unproven. Raising VEGF increases vessels around follicles in mice and minoxidil raises VEGF in cultured cells, but no study shows VEGF-marketed products improve scalp blood flow or hair loss in people.
Is Vascular Endothelial Growth Factor (VEGF) available as a topical treatment, or is it only stimulated indirectly? VEGF is not available as a topical treatment for hair loss.
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learn Platelet-Rich Plasma

What is platelet-derived growth factor beta polypeptide (PDGF-BB), and does it stimulate new hair growth? PDGF-BB is a growth factor that signals to dermal papilla cells and promotes blood-vessel formation; mouse studies report it can push follicles into the growth phase, and human evidence comes only indirectly from PRP trials. No PDGF product is approved for hair restoration and there is no published human trial of PDGF-BB on its own.

learn Stem Cell Factor

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