4 citations
,
December 2022 in “Skin Research and Technology”
This study found that downregulation of Sonic hedgehog signaling may promote HPV replication and wart formation by inducing cell cycle arrest in keratinocytes.
September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”
This study found that zebrafish and stickleback fish use similar genetic programs for tooth regeneration, despite differences in their dental structures.
This study used whole-genome resequencing to analyze genetic diversity and selection in 17 rabbit breeds, identifying genes linked to traits like coat color and body size, which could inform breeding and conservation efforts.
39 citations
,
March 2008 in “Journal of biological chemistry/The Journal of biological chemistry”
This study found that GLI2 plays a key role in activating follistatin, an activin/BMP antagonist, in response to hedgehog signaling in human epidermal cells, with implications for hair follicle development and basal cell carcinoma.
This study identified significant gene expression differences in human basal cell carcinoma, including up-regulation of zincfinger encoding genes, which are not entirely reflected in current mouse models.