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Glossary Androgenetic Alopecia

genetic hair loss influenced by androgens, often hereditary

Androgenetic Alopecia, commonly known as Male Pattern Baldness or Female Pattern Baldness, is a genetic condition characterized by progressive hair thinning and loss. It is influenced by androgens (male hormones) and typically follows a recognizable pattern, such as a receding hairline in men and diffuse thinning on the crown in women. This condition is the most common cause of hair loss, affecting both genders, and is often hereditary.

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Research

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Update on the Genetics of Androgenetic Alopecia, Female Pattern Hair Loss, and Alopecia Areata: Implications for Molecular Diagnostic Testing

research Update on the Genetics of Androgenetic Alopecia, Female Pattern Hair Loss, and Alopecia Areata: Implications for Molecular Diagnostic Testing

11 citations , November 2012 in “Seminars in Cutaneous Medicine and Surgery”

This review summarizes current understanding and genetic insights into androgenetic alopecia, female pattern hair loss, and alopecia areata, noting the potential future role of molecular diagnostics, but it reports no new clinical results.

research Molecular Genetics of Alopecias

9 citations , January 2015 in “Current problems in dermatology”

This review highlights recent genetic research advancements in understanding hereditary hair diseases but reports no new study results, emphasizing the identification of genes related to both monogenic and polygenic hair disorders.

research Atrichia with papular lesions in Syrian siblings exposing global diagnostic challenges in genetic alopecia: A rare case report

May 2026 in “Journal of International Medical Research”

This case report describes a 4-year-old patient with complete hair loss and keratotic papules, leading to a diagnosis of atrichia with papular lesions, underscoring diagnostic challenges in resource-limited settings and suggesting a clinical framework for identifying this condition, especially in consanguineous families.

research Genetic Insights into Acne, Androgenetic Alopecia, and Alopecia Areata: Implications for Mechanisms and Precision Dermatology

October 2025 in “Cosmetics”

This study examines the genetic underpinnings of chronic dermatological conditions like acne, androgenetic alopecia, and alopecia areata, concluding that a deep understanding of these mechanisms can advance patient-specific treatments and inform cosmetic practices related to skin and hair health.

research Androgenic alopecia in men: the significance of genetic, hormonal and metabolic factors (prospective cohort comparative study)

December 2022 in “Rossiiskii Zhurnal Kozhnykh i Venericheskikh Boleznei”

In this study, researchers found that genetic and non-genetic factors, including deficiencies in micronutrients like zinc and vitamins, play varying roles in the development of androgenetic alopecia in men.

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Community Join

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community Needle mesotherapy in the treatment of androgenic alopecia

5 upvotes 3 months ago

Mesotherapy with vitamins is unlikely to effectively treat genetic hair loss and may be a waste of money. Taking 0.25 mg of finasteride daily is likely sufficient to slow hair loss, as it provides similar benefits to higher doses with fewer side effects.

community Iron Deficiency Hair Loss vs Androgenetic Alopecia

5 upvotes 3 years ago

Iron deficiency can mimic androgenetic alopecia (AGA) and cause hair loss, but it is rare in men. Recovery is possible with supplements if iron deficiency is the cause, but genetic hair loss may still progress.

community Is trichogram a good thing for testing genetic hair loss

2 upvotes 7 months ago

A dermatologist checked for hereditary hair loss using blood tests and plans to perform a trichogram. The user had slightly low Vitamin D3 levels, and the trichogram may help confirm androgenetic alopecia.

community Pilose antler extracts promotes hair growth in androgenetic alopecia mice by activating hair follicle stem cells via the AKT and Wnt pathways

11 upvotes 2 years ago

Pilose antler extracts may promote hair growth in androgenetic alopecia by activating hair follicle stem cells through the AKT and Wnt pathways. However, results in mice may not directly apply to humans due to differences in genetic and biochemical conditions.

community Female diffuse hair loss on spiro with irregular periods (photos) + genetic hair loss

in Female 16 upvotes 1 year ago

A 34-year-old woman is experiencing diffuse hair loss and irregular periods, possibly due to long-term spironolactone use. She is considering minoxidil and finasteride for treatment and seeking medical advice for androgenic alopecia and hormonal imbalances.

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Learn

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learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Hair Transplant

What causes male pattern baldness? Male pattern baldness is caused by genetic sensitivity to the hormone DHT.

learn Overview

learn HMI-115

much-hyped research compound targeting prolactin receptor in scalp

learn SCUBE3

a signaling molecule from dermal papilla cells being actively researched

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Vitamin B1

Thinning hair over time? It might not just be genetics: lack of B1 and B2 could be silently working against you. There is no verified human trial showing that B1 or B2 deficiency causes thinning hair or that correcting it regrows hair; a 2019 review concludes the role of micronutrients in hair loss is real but unclear and still needs controlled trials.

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