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    GlossaryGenetic Androgenetic Hair Thinning

    genetic condition causing gradual hair loss influenced by androgens

    Genetic Androgenetic Hair Thinning, also known as Androgenetic Alopecia, is a common form of hair loss influenced by genetic factors and the presence of androgens (male hormones). It typically manifests as a gradual thinning of hair on the scalp, often following a recognizable pattern such as a receding hairline in men or diffuse thinning in women.

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      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn SCUBE3

      a signaling molecule from dermal papilla cells being actively researched

      learn Dutasteride

      Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity

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      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community How effective is spironolactone?

      in Transgender  6 upvotes 2 years ago
      A 21-year-old MTF individual is experiencing rapid hair thinning and is currently on estradiol valerate. They are inquiring about the effectiveness of spironolactone for hair loss, despite being aware of its serious side effects.

      community Are permanent hair gains even possible?

      in Chat  14 upvotes 1 month ago
      Hair regrowth from treatments like minoxidil, RU58841, and finasteride is not permanent; stopping these treatments typically results in hair loss resuming. Beard hair can become permanent with minoxidil use, unlike scalp hair, which requires ongoing treatment to maintain gains.