22 citations
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August 2013 in “PLOS ONE” The method safely and efficiently delivers genes to the skin but may not work for conditions needing high levels of gene products.
6 citations
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June 2019 in “Biotechnology Letters” Gene therapy shows promise for improving wound healing, but more research is needed for human use.
15 citations
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June 2021 in “Journal of Genetic Engineering and Biotechnology” Biomaterials can improve non-viral gene delivery by enhancing DNA uptake and reducing toxicity.
15 citations
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February 2021 in “Cells” Transfected cells with VEGF and FGF2 genes improve skin wound healing by enhancing blood flow and regeneration.
Various substances, quitting smoking, and certain topical applications can enhance the survival of skin flaps used in surgery. Oxygen-free radicals play a role in tissue injury, but certain treatments can have beneficial effects.