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the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil
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an anticonvulsant repurposed for hair loss via histone inhibition
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Research
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research Topical Gene Electrotransfer to the Epidermis of Hairless Guinea Pig by Non-Invasive Multielectrode Array
The method safely and efficiently delivers genes to the skin but may not work for conditions needing high levels of gene products.
research Basic Concepts, Current Evidence, And Future Potential For Gene Therapy In Managing Cutaneous Wounds
Gene therapy shows promise for improving wound healing, but more research is needed for human use.
research Influence of Recombinant Codon-Optimized Plasmid DNA Encoding VEGF and FGF2 on Co-Induction of Angiogenesis
Transfected cells with VEGF and FGF2 genes improve skin wound healing by enhancing blood flow and regeneration.
research Physical and Mechanical Cues Affecting Biomaterial-Mediated Plasmid DNA Delivery: Insights Into Non-Viral Delivery Systems
Biomaterials can improve non-viral gene delivery by enhancing DNA uptake and reducing toxicity.
research Ischemic Skin Flaps: What to Use to Save Them? A Narrative Review
Various substances, quitting smoking, and certain topical applications can enhance the survival of skin flaps used in surgery. Oxygen-free radicals play a role in tissue injury, but certain treatments can have beneficial effects.
Community Join
5 / 453 resultscommunity 22 years since the last major development
The conversation discusses the lack of significant advancements in hair loss treatments since the introduction of finasteride 22 years ago, with many expressing frustration over the failure of new projects and skepticism about future developments. Some users mention hair transplants and other potential alternatives like Alfatradiol and Fluridil, but acknowledge finasteride's dominance in the market due to its effectiveness and affordability.
community Father has decent amount of hair but im balding ?
A user is concerned about male pattern baldness despite their father having hair. Replies suggest visiting a dermatologist and considering finasteride or dutasteride, as natural methods are ineffective.
community Where does time go? Turning 30 soon and been on treatment for 8 years.
User started fin/min/niz at 23, switched to Dut at 24, and has been on treatments for 7 years. Despite occasional doubts, hair improved and user advises sticking with treatments.
community CRISPR treatment for AGA on the horizon after approval for blood disorders
CRISPR treatments for blood disorders have been approved, leading to discussions about its potential for treating hair loss (AGA). A study showed that editing a gene related to DHT sensitivity could lead to hair regrowth, suggesting CRISPR may eventually be used for AGA, but it's expected to be expensive and not soon available.
community What should we lookout for in the near future for hairloss?
The user is using finasteride and minoxidil for hair loss but is looking for new treatments. Pyrilutamide and GT20029 are potential future treatments, with Pyrilutamide expected next year and GT20029 possibly by 2027.