research Identification of novel mutation in theHRgene responsible for atrichia with papular lesions in a Pakistani family
Researchers found a new mutation in the HR gene causing hair loss and skin bumps in a Pakistani family.
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research Whole genome sequencing analysis of alpaca suggests TRPV3 as a candidate gene for the suri phenotype
This study identified a gene variant in the TRPV3 gene that may explain the suri alpaca phenotype, characterized by longer and less crimped fleece, suggesting this variant's involvement in the development of these hair characteristics compared to the huacaya phenotype.
research The retarded hair growth ( rhg ) mutation in mice is an allele of ornithine aminotransferase ( Oat )
This study discovered that a specific G to C mutation in the ornithine aminotransferase gene is linked to the retarded hair growth phenotype in mice and may serve as a model for human gyrate atrophy.
research Two Different Mutations in the Same Codon of a Type II Hair Keratin (hHb6) in Patients with Monilethrix
Mutations in the hHb6 gene cause the hair disorder monilethrix.
research A mutation in MAP2 is associated with prenatal hair follicle density
In this study, a missense mutation in the MAP2 gene was found to be associated with reduced hair follicle density, leading to the hairless phenotype in pigs.
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5 / 1000+ resultscommunity Non-prescription topical supportive treatments (e.g. caffeine, alfatradiol, The Ordinary Serum, Zix, etc) in addition to the big 3/4???
Adding non-prescription topicals like alfatradiol and Zix to a standard fin/min/niz regimen may help with scalp inflammation and shedding, but their long-term effectiveness varies. Zix is recommended for reducing scalp inflammation and enhancing the effectiveness of other treatments.
community Do the more newer gen topical retinoids e.g. tazarotene outperform tretinoin in inducing follicular sulfotransferase activity?
Tazarotene may outperform tretinoin for hairline treatment with minoxidil, but lacks evidence. Tretinoin is recommended for the scalp, while tazarotene can be used on the face.
community Is anyone here using lower concentrations of topical finasteride (e.g., 0.005-0.05% range) and seeing results?
Users discuss the effectiveness of low-dose topical finasteride (0.005-0.05%) for hair loss, often combined with minoxidil. Some report stable results or new growth, but it's unclear if improvements are due to finasteride or minoxidil.
community Has anyone here tried Vichy Dercos Aminexil Clinical R.E.G.E.N. Booster?
The conversation discusses the effectiveness of Vichy Dercos Aminexil Clinical R.E.G.E.N. Booster for hair shedding and thinning. The main ingredient, Aminexil, is compared to Minoxidil, and the user seeks real experiences to determine its efficacy.
community Does anyone get blood tests while taking Finasteride to ensure thing are working appropriately (e.g. DHT is decreasing and estrogen isn't increasing significantly)
People are discussing the use of finasteride for hair loss and the importance of hormonal blood testing to monitor effects like changes in DHT and estradiol levels. Some users also mention using minoxidil and the potential side effects of estradiol, such as gynecomastia, especially at higher doses.
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