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In this review, researchers discussed the development, challenges, and future prospects of using CRISPR/Cas9 gene editing technology in livestock breeding, highlighting its current limitations in precise gene insertion and off-target effects, particularly in large livestock like cashmere goats.

The researchers reviewed the status, challenges, and future prospects of CRISPR/Cas9-mediated gene-editing technology in livestock breeding, noting its benefits and highlighting concerns about low efficiency in inserting foreign genes and off-target effects.

Chicken feather gene mutation helps understand human hair disorders.

In this study, the authors observed that a 48-year-old woman developed a cutaneous pseudolymphoma in the earlobes linked to metallic debris from ear piercing, which histologically mimicked lymphoma but was interpreted as a reactive condition.

This study found that inserting the Tβ4 gene into cashmere goats increased cashmere yield by 74.5% without compromising quality, suggesting potential economic benefits for goat breeding.