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research From a stem-cell–centered to a niche-centered view: the core role of collagen networks in hair loss and hair follicle miniaturization

May 2026 in “Frontiers in Cell and Developmental Biology”

In this study, researchers suggest that hair follicle miniaturization in conditions like androgenetic alopecia may result from impaired conversion of quiescent stem cells to progenitor cells, influenced by the follicular niche, its collagen network, and various mechanical constraints.

research Lichen planopilaris versus frontal fibrosing alopecia: histopathologically distinct diseases or not?

March 2026 in “Anais Brasileiros de Dermatologia”

Lichen planopilaris and frontal fibrosing alopecia are likely distinct diseases with different tissue involvement.

research Fox-Fordyce Disease

5 citations , February 2016 in “Sultan Qaboos University medical journal”

This case report describes a patient with a severe pruritic rash and hair loss in both axillary regions, with no fluorescence under a Wood's lamp and hair follicle-centred papules observed through dermoscopy.

research Segmental vitiligo with confetti-like peripheral depigmentation.

December 2018 in “European Journal of Pediatric Dermatology/PD. European journal of pediatric dermatology”

This article discusses the potential involvement of hair follicle melanocytes in follicular vitiligo, noting a pattern of depigmentation centered on follicles and supported by inflammatory infiltrates, without reporting new clinical results.

research The most recent advances in understanding and managing hidradenitis suppurativa

28 citations , August 2020 in “F1000Research”

This review discusses the multifactorial pathogenesis of hidradenitis suppurativa and calls for more diverse, standardized clinical trials to improve treatment and understanding of dietary influences, reporting no new results.

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community Interesting new publication suggesting that MPB should be assessed as a early warning sign for type-2 diabetes.

15 upvotes 8 years ago

Male pattern baldness (MPB) may be an early warning sign for type 2 diabetes due to its association with insulin resistance. Treatments discussed include testosterone therapy and finasteride, which affects hormone levels related to hair loss and insulin sensitivity.

community Why don’t more people use hair fibers?

in Product 527 upvotes 10 months ago

Hair fibers can effectively cover thinning hair when used with minoxidil and hairspray but require daily application and can be inconvenient in certain conditions. Some users prefer treatments like finasteride, dutasteride, microneedling, or wigs due to the maintenance and limitations of hair fibers.

community Researchers working on ways to regenerate lost hair from stem cells identified a recipe for normal hair regeneration in the lab. “A method for cyclical regeneration of hair follicles from hair follicle stem cells and will help make hair follicle regeneration therapy a reality in the near future.”

263 upvotes 5 years ago

Hair loss treatments like finasteride, minoxidil, and hair transplants have side effects and limitations. There is hope for future advancements in stem cell therapy and hair follicle regeneration, though skepticism about their effectiveness and timeline persists.

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