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Glossary Fisetin

naturally occurring flavonoid with potential hair growth benefits

Fisetin is a naturally occurring flavonoid found in various fruits and vegetables, such as strawberries, apples, and onions. It has been studied for its potential antioxidant, anti-inflammatory, and anti-cancer properties, and recent research suggests it may also promote hair growth and protect against hair loss by modulating certain cellular pathways and reducing oxidative stress.

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Research

5 / 113 results

research Fisetin Promotes Hair Growth by Augmenting TERT Expression

22 citations , October 2020 in “Frontiers in Cell and Developmental Biology”

This study found that resveratrol and fisetin promoted hair growth in mice by inducing telomerase reverse transcriptase expression, which activates hair follicle stem cells and transitions follicles from a resting to a growth phase.

research Exosomes Derived from Fisetin-Treated Keratinocytes Mediate Hair Growth Promotion

9 citations , June 2021 in “Nutrients”

In this study, fisetin applied to the dorsal skin of mice activated hair follicle stem cells through exosome secretion from keratinocytes, promoting hair growth.

research Potential Biomolecule Fisetin: Molecular and Pharmacological Perspectives

March 2024 in “Current materials science”

This study explores the various properties of the flavonoid fisetin, highlighting its potential therapeutic applications due to its ability to modulate numerous biological pathways, suggesting benefits in conditions like inflammation, cancer, and neurodegenerative diseases.

Fisetin Promotes Differentiation, Inhibits Proliferative and Inflammatory Responses in Cultured Human Cells and Alleviates Psoriasiform Dermatitis in Mice

research 713 Fisetin promotes differentiation, inhibits proliferative and inflammatory responses in cultured human cells and alleviates psoriasiform dermatitis in mice

April 2017 in “Journal of Investigative Dermatology”

This study found that fisetin, a dietary flavonoid, significantly improved psoriasiform skin lesions in mice by promoting cell differentiation, inhibiting proliferation, and modulating inflammatory responses.

research 471 Senolytic Potential of Fisetin and ABT Compounds in Dermal Fibroblasts

November 2025 in “Journal of Investigative Dermatology”

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community Anti-oxidants that reverse hairloss?

86 upvotes 5 years ago

Resveratrol and fisetin, found in red wine and strawberries, may promote hair growth by affecting hair follicle cells. Users discuss various treatments, including natural remedies like saw palmetto and topical applications, with mixed opinions on their effectiveness compared to pharmaceuticals like finasteride.

community Ways to prevent hair from becoming grey or delaying the greying of hairs? (Have You Heard of Catalase!?)

23 upvotes 1 year ago

Catalase is discussed as a potential treatment for delaying or reversing grey hair, but no reliable medicine currently exists. Other mentioned treatments include Imatinib, senolytics like Quercetin and Fisetin, He Shou Wu, Argan oil, and reishi mushroom extract, though their effectiveness varies.

community Topical fin vehicle other than minox

4 upvotes 4 years ago

The conversation is about using a topical finasteride solution without minoxidil to avoid side effects, with suggestions to use alternatives like a PG solvent or Stemox. There is also a mention of mixing finasteride with fisetin powder in the solvent.

community Best, possible, or experimental growth agonists that AREN'T MINOXIDIL.

4 upvotes 5 years ago

Various hair growth treatments were discussed, including microneedling, bimatoprost, setipiprant, stemoxydine, PGE2, CB-03-01, WNT Beta-Catenin upregulators, KY19382, topical estrogen, IGF-1, GH, MK-677, oral castor oil, fisetin, resveratrol, cetrizine, and lactic acid. Users shared experiences and sources for these treatments, with some expressing interest in topical solutions and others noting the lack of FDA approval or scientific evidence for certain options.

community Targeting multiple AGA mechanisms with commonly available substances

4 upvotes 7 years ago

The conversation discusses using a multimodal approach to treat androgenic alopecia, including substances like gamma-linolenic acid, DHA, sulforaphane, melatonin, cetirizine, astaxanthin, fisetin, apigenin, curcumin, limonene, genistein, and berberine. Users also mention using ketoconazole, minoxidil, and low-level laser therapy (LLLT) as part of their hair loss treatment regimens.

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