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learn Follistatin

How does follistatin compare to finasteride or dutasteride for treating androgenic alopecia? Finasteride and dutasteride are prescription drugs with large controlled trials showing they lower DHT and slow androgenic hair loss, at the cost of documented hormonal side effects; follistatin targets a different, regenerative pathway but has only one small phase 1 human trial behind it, so it is experimental with unknown safety rather than a comparable alternative.

learn Dutasteride

Heavy duty finasteride that comes with higher risks

Dutasteride: Why don't some doctors prescribe it if it's stronger than finasteride? Some doctors avoid prescribing dutasteride due to its higher risk of side effects.

learn Setipiprant

What is Setipiprant and how does it differ from DHT blockers like finasteride or dutasteride? Setipiprant blocks the prostaglandin D2 receptor DP2 rather than the DHT pathway that finasteride and dutasteride act on. The one published human trial — a 169-man, 24-week phase 2a study at 2,000 mg a day — reported no statistically significant improvement in hair density over placebo, and setipiprant is not an approved hair-loss medicine anywhere.

learn Finasteride

Frontline, gold standard treatment for combatting androgenic alopecia

Is Finasteride unbeatable or are there equally powerful alternatives? Trials report finasteride as the single medication with the strongest measured effect in male androgenetic alopecia, while dutasteride, minoxidil, topical finasteride, PRP, LLLT and microneedling all have supporting studies and are often reported to work better in combination. Finasteride, dutasteride and oral minoxidil are prescription-only, and several of these uses are off-label.
Is finasteride safe? Studies report that most men tolerate finasteride 1 mg, but case series, regulatory labelling and patient reports describe sexual, mood and cognitive effects that some say persisted after stopping, and how often that happens is not established. It is a prescription-only medicine and is contraindicated in pregnancy.

learn Mesotherapy

technique to inject very small amounts of beneficial chemicals into the scalp

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Community Join

5 / 1000+ results

community 5 years on topical finasteride, 3.5 years on oral minoxidil; now changing from finasteride to dutasteride

in Finasteride/Dutasteride 3 upvotes 3 weeks ago

A 66-year-old male experienced significant hair regrowth using topical finasteride for 5 years and oral minoxidil for 3.5 years, with no side effects. He is now switching from finasteride to topical dutasteride 0.1% to potentially improve results further.

community Is it possible for topical finasteride to be more effective than dutasteride for some people?

in Finasteride/Dutasteride 5 upvotes 1 month ago

Topical finasteride may be more effective than dutasteride for some individuals, with some users reporting better results with finasteride. Combining finasteride and dutasteride in a topical formula is questioned for its effectiveness.

community Adding dutasteride to fin regimen

in Finasteride/Dutasteride 5 upvotes 1 month ago

The conversation discusses adding dutasteride to a finasteride regimen for potential hair regrowth or thickening. Some users report positive results with the combination, while others caution about side effects like reduced libido.

community Finasteride stopped working. Losing ground on Dutasteride.

in Finasteride/Dutasteride 17 upvotes 4 months ago

The user started with Finasteride at 19, added Dutasteride and Minoxidil at 26, but continues to experience hair loss. Suggestions include checking health markers, considering genetics, and possibly increasing Minoxidil dosage.

community 1.5 years on 1.2 Mg fin. Minimal results. Recently switched to dutasteride.

in Finasteride/Dutasteride 23 upvotes 4 months ago

The user has been on 1.2 mg finasteride for 1.5 years with minimal results and recently switched to dutasteride. Suggestions include adding minoxidil, derma rolling, and considering dietary changes to improve hair health.

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Research

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research The Use of Oral Dutasteride, Minoxidil, and Finasteride for Treating Endocrine Therapy-Induced Hair Loss from Breast Cancer Treatment: A Case Series Study

November 2025 in “JAAD Case Reports”

Oral dutasteride, minoxidil, and finasteride may help reduce hair loss in breast cancer survivors, but more research is needed.

research Review: Dutasteride, fesoterodine, and finasteride are beneficial for lower urinary tract symptoms in older patients

October 2015 in “Annals of Internal Medicine”

Dutasteride, fesoterodine, and finasteride help older patients with urinary issues.

research The Effect of 5α-Reductase Inhibition with Dutasteride and Finasteride on Semen Parameters and Serum Hormones in Healthy Men

195 citations , February 2007 in “The Journal of Clinical Endocrinology and Metabolism”

In this study, administering 5alpha-reductase inhibitors reduced dihydrotestosterone levels and was associated with mild, reversible decreases in semen parameters in healthy men.

The Effect of 5α-Reductase Inhibition With Dutasteride and Finasteride on Bone Mineral Density, Serum Lipoproteins, Hemoglobin, Prostate Specific Antigen, and Sexual Function in Healthy Young Men

research The Effect of 5α-Reductase Inhibition With Dutasteride and Finasteride on Bone Mineral Density, Serum Lipoproteins, Hemoglobin, Prostate Specific Antigen and Sexual Function in Healthy Young Men

72 citations , April 2008 in “The Journal of urology/The journal of urology”

This study found that 1-year use of 5alpha-reductase inhibitors, dutasteride or finasteride, significantly lowered dihydrotestosterone levels without adversely affecting bone density, lipids, or hemoglobin in normal men.

Human Type 3 5α-Reductase Is Expressed in Peripheral Tissues at Higher Levels Than Types 1 and 2 and Its Activity Is Potently Inhibited by Finasteride and Dutasteride

research Human type 3 5α-reductase is expressed in peripheral tissues at higher levels than types 1 and 2 and its activity is potently inhibited by finasteride and dutasteride

45 citations , August 2010 in “Hormone Molecular Biology and Clinical Investigation”

This study found that SRD5a-3 is a highly efficient enzyme for converting hormones into androgens, with dutasteride being a much more potent inhibitor of SRD5a-3 than SRD5a-2.

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