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This study found that overexpression of an enzyme in transgenic mice led to distorted polyamine levels, resulting in permanent hair loss and female infertility.

This systematic review found that estrogen deficiency in postmenopausal women leads to structural and symptomatic changes in genital and cutaneous tissues, with local estrogen therapy providing short-term benefits, while evidence for device-based treatments remains limited and requires larger trials.

Hormonal treatment in transgender women reduces semen quality, but stopping treatment may improve it.

This study explored treatment options used by women with PCOS and found that many prefer lifestyle modifications and alternative therapies like low-carb, high-protein, or low-calorie diets alongside supplements such as vitamin D, spearmint tea, omega-3s, and probiotics, often in addition to prescription medications like Metformin.