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research Wound Regeneration Deficit in Rats Correlates with Low Morphogenetic Potential and Distinct Transcriptome Profile of Epidermis

21 citations , January 2018 in “Journal of Investigative Dermatology”

Rats can't grow new hair follicles after skin wounds, unlike mice, due to differences in gene expression and response to WNT signaling.

research Through the Lens of Hair Follicle Neogenesis: A New Focus on Mechanisms of Skin Regeneration After Wounding

28 citations , October 2019 in “Seminars in Cell & Developmental Biology”

Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.

research Optimal Skin Regeneration After Full Thickness Thermal Burn Injury in the Spiny Mouse, Acomys Cahirinus

39 citations , June 2018 in “Burns”

The spiny mouse can fully regenerate skin after burns, unlike the lab mouse.

research Comparative Transcriptomic Analysis of Dermal Wound Healing Reveals De Novo Skeletal Muscle Regeneration in Acomys Cahirinus

24 citations , May 2019 in “PLOS ONE”

The African spiny mouse can fully regenerate its muscle without scarring, unlike the common house mouse.

research Comparative Regenerative Biology of Spiny (Acomys Cahirinus) and Laboratory (Mus Musculus) Mouse Skin

37 citations , February 2019 in “Experimental Dermatology”

Spiny mice are better at regenerating hair after injury than laboratory mice and could help us understand how to improve human skin repair.

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community Another molecular pathway to promote scarless healing and regenerate hair follicles

in Research/Science 13 upvotes 2 months ago

Carnosic acid in rosemary extract may enhance skin repair and promote hair follicle regeneration. It could be used alone or with verteporfin for scarless healing after dermal wounding.

community Sucess story for you guys, pics are 10+ years apart.

in Progress Pictures 311 upvotes 2 years ago

A user shared a success story showing hair regrowth over 10 years, attributing it to quitting creatine and taking 0.5mg finasteride. Some commenters were skeptical about creatine's impact, while others inquired about side effects, and the original poster reported no negative effects from finasteride.

community Saw a local dermatologist recently, they suggested switching from Finasteride to Dutasteride…

in Finasteride/Dutasteride 20 upvotes 6 months ago

The user experienced hair loss and initially saw improvement with Finasteride but is now considering switching to Dutasteride due to lack of recent results. They plan to add topical Minoxidil and are awaiting biopsy results to determine the cause of hair loss.

community PP405: Regrows Hair In 8 Weeks. Is This The Miracle Cure?

in Research/Science 165 upvotes 1 month ago

PP405 is considered as a potential hair regrowth treatment, but users are skeptical due to past product failures. They compare it to Minoxidil and Finasteride, questioning its effectiveness and the intentions of pharmaceutical companies.

community Verteporfin day 119 update - donor hair regeneration human trial

in Research/Science 148 upvotes 3 years ago

A human trial of verteporfin, a drug that can inhibit wound healing by scarring and promote regeneration of original tissue and hair follicles to provide an unlimited source for hair transplants; people discussed the potential of this drug and how it could be rolled out in mainstream with more doctors getting on board.

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