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research LB1605 3D imaging of cleared ex vivo normal human skin, skin appendages and psoriasiform skin lesion using light-sheet microscopy

August 2018 in “Journal of Investigative Dermatology”

This study found that combining optical clearing methods with light-sheet fluorescence microscopy allows detailed 3D visualization of normal and pathological human skin biopsies, revealing differences in epidermal thickness and volume.

research Electromagnetic Imaging of Subdermal Human Hair Follicles In Vivo

1 citations , May 2016 in “Journal of nature and science”

In this study, a method using nano-sized iron particles successfully captured images of sub-dermal hair follicles, showing comparable size and shape to those removed from the skin.

research Ex-vivo measurement of scalp follicular infundibulum delivery of zinc pyrithione and climbazole from an anti-dandruff shampoo

12 citations , May 2017 in “Journal of pharmaceutical and biomedical analysis”

In this study, researchers developed a method using scalp cyanoacrylate biopsy and advanced imaging techniques to effectively measure and visualize the distribution of anti-dandruff shampoo ingredients zinc pyrithione and climbazole within the scalp follicular infundibulum.

research Mapping cell dynamics in human ex vivo hair follicles suggests pulling mechanism of hair growth

November 2025 in “Nature Communications”

This study used a 3D live imaging system to map cell dynamics in human hair follicles, revealing patterns of cell movement and division that help explain hair fiber extrusion during hair growth.

research Epidermal/Dermal Separation Techniques and Analysis of Cell Populations in Human Skin Sheets

1 citations , December 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

This review discusses various methods for processing and separating human skin samples for research purposes, evaluating factors like processing time and cell viability, but reports no new experimental findings.

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community How do you think Shah Rukh Khan maintains his full head of hair at 60?

453 upvotes 9 months ago

Shah Rukh Khan's hair at 60 is attributed to genetics, with speculation about using finasteride, minoxidil, or hair transplants. Some believe it's due to good genes, while others think he might use treatments or have had hair procedures.

community Everything you ever wanted to know about Pelage Pharma's PP405: how it works and what to expect

126 upvotes 3 months ago

PP405 may encourage earlier hair growth and slightly increase visible hair count but does not reverse hair follicle miniaturization in male pattern baldness. It does not address damage to the dermal papilla or broken Wnt signaling.

community Story time! The Great Unbalding (PP405)

230 upvotes 11 months ago

PP405 is a promising new hair loss treatment that may reactivate dormant hair follicles without side effects. It could surpass traditional treatments like minoxidil and finasteride if successful in further trials.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 year ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community 0.5mg Dutasteride promotes more “regrowth” than 5mg oral Minoxidil

in Research/Science 117 upvotes 2 years ago

Dutasteride promotes more hair regrowth than Minoxidil. Users discuss combining treatments for better results and share personal experiences with side effects.

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