4 citations
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January 2019 in “PubMed” This study found that low dose valproate monotherapy in epileptic children commonly leads to side-effects like weight gain and decreased appetite, especially among younger patients.
January 2016 in “International journal of clinical pediatrics” In this study, ultrastructural examination of hair in children treated with valproic acid showed a normal hair surface and cuticular pattern, despite reported hair changes with the drug.
4 citations
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October 1993 in “PubMed” This study observed that while valproic acid treatment in children led to occasional mild clinical and laboratory side effects, no correlation with drug plasma levels was found.
1 citations
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December 1982 in “PubMed” In this study, sodium valproate as monotherapy stopped seizures in 50% of epileptic children and was most effective in primary generalized and photosensitive epilepsies with notable side effects.
16 citations
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October 1994 in “PubMed” This review, drawing on literature and personal experience, suggests that sodium valproate is a safe and effective antiepileptic drug for various epileptic conditions in children and adults, including the elderly.
