Tolerance to and Unwanted Effects of Valproate Sodium

October 1994 in “ PubMed ”

Despland Pa

valproate sodium hair loss anticonvulsant hepatotoxicity VPA

TLDR Sodium valproate is a safe and effective epilepsy drug with manageable side effects.

The review discussed the use of sodium valproate (VPA) as an antiepileptic drug since 1967, highlighting its safety and effectiveness in treating epilepsy across various age groups. VPA was noted for having fewer neurological side effects and minimal impact on cognitive function compared to other antiepileptic drugs like phenytoin and phenobarbital. Common side effects specific to VPA included weight gain, tremor, and hair loss, which could be managed by adjusting the dosage. Gastrointestinal disturbances were reduced with enteric or 'chrono' VPA tablets, and a single daily dose regimen improved patient compliance without increasing toxicity. Rare cases of fatal hepatotoxicity were reported as an idiosyncratic reaction unrelated to dosage.

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community Better Than Minoxidil? Topical Sodium Valproate

in Research/Science 51 upvotes 10 months ago

Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

community Topical Valproic acid/sodium valproate — has anyone tried this?

in Question 2 upvotes 5 years ago

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community Novel Formulation To Put An End To Hair Loss Once And For All.

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community New & Improved Hair Growth Stack for Maximum Results

in Treatment 5 upvotes 10 months ago

A user shared a hair growth stack using minoxidil sulfate, valproic acid, bimatoprost, blue copper peptide, and other ingredients, emphasizing a gel-based formula for better skin tolerance. Another user suggested adding a 5-alpha-reductase inhibitor like finasteride or dutasteride for more effective long-term results.

community VDPHL-01 is Overrated and Ridiculous. This is just Oral Minoxidil.

in Research/Science 21 upvotes 10 months ago

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community Sorry yall I cheated 😵‍💫 1 year fin + hrt

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Hair regrowth and gender transition using finasteride, estrogen, and spironolactone. Significant hair regrowth and personal transformation were achieved through hormone replacement therapy.

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research Tolerance to and Unwanted Effects of Valproate Sodium

16 citations , October 1994 in “PubMed”

Sodium valproate is a safe and effective epilepsy drug with manageable side effects.