10 citations
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September 2008 in “Andrologia” In this study, treatment with finasteride altered the expression patterns of antioxidant enzymes in the epididymis of rats, potentially affecting its protective function for spermatozoa.
2 citations
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September 2017 in “Archives of Medical Science” The researchers reported that finasteride treatment in male rats may lead to changes in antioxidant enzyme activity in their offspring's epididymis, potentially affecting sperm maturation.
104 citations
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June 2020 in “Journal of Endocrinology” This study suggests that in rats, maternal hyperandrogenism and insulin resistance lead to activation of ferroptosis in the gravid uterus and placenta, mediated by different molecular and cellular mechanisms.
January 2025 in “Applied Sciences” This review examines sulforaphane's interactions with hormone-mediated health conditions, focusing on gender-specific health issues, but reports no new original research findings.
3 citations
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April 2021 in “Journal of Medicinal Chemistry” This study suggests that finasteride may inhibit the enzyme PNMT, potentially contributing to its sexual and psychological side effects.